Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	121765
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Chemotherapy regimens with immunotherapy in advanced gastric cancer: A prognostic study using Cox modeling
Manuscript Source	Unsolicited Manuscript
All Author List	Shao-Wei Jiang, Chen-Guang Zhang, Ke-Di Wang, Kun-Peng Shang, Peng-Jie Yu and Huan-Li Wang
Funding Agency and Grant Number	Funding Agency Grant Number Qinghai Provincial Science and Technology Program No. 2023-ZJ-787
Corresponding Author	Huan-Li Wang, Professor, Qinghai University Affiliated Hospital Tumor Day Chemotherapy Center, Qinghai University Affiliated Hospital, No. 29 Tongren Road, Chengxi District, Xining 810000, Qinghai Province, China. 229572196@qq.com
Key Words	Gastric cancer; Neoadjuvant therapy; Least absolute shrinkage and selection operator; Cox regression; Prognostic model
Core Tip	This study compares three commonly used neoadjuvant regimens (S-1 combined with oxaliplatin and sintilimab, plus oxaliplatin and S-1, and oxaliplatin plus leucovorin and fluorouracil) in advanced gastric cancer and demonstrates that the addition of a programmed cell death protein 1 inhibitor improves pathological response without increasing unacceptable toxicity. Furthermore, a prognostic model integrating treatment response (Response Evaluation Criteria in Solid Tumors 1.1 and tumor regression grade) with clinicopathological factors provides reliable prediction of progression-free survival, highlighting the value of response-based variables in individualized risk stratification.
Citation	Jiang SW, Zhang CG, Wang KD, Shang KP, Yu PJ, Wang HL. Chemotherapy regimens with immunotherapy in advanced gastric cancer: A prognostic study using Cox modeling. World J Gastrointest Oncol 2026; In press

Received	2026-04-01 03:37
Peer-Review Started	2026-04-01 03:42
First Decision by Editorial Office Director	2026-04-16 07:49
Return for Revision	2026-04-16 08:08
Revised	2026-04-20 17:05
Publication Fee Transferred	2026-04-22 04:22
Second Decision by Editor	2026-06-01 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-02 07:23
Articles in Press	2026-06-02 07:23
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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