Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	121790
DOI	10.4291/wjgp.121790
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Accuracy of non-invasive tests for diagnosing liver fibrosis and steatosis: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Saurin R Shukla, Mirza Amer Ali Baig, Arika Pareek, Namita Johari, Yeshika Thapa, Beulah Blessy Kumpati, Shreya Mahesh Nirmal, Ifrah Ayesha Imdad, Durnave Azid, Eniola Aina and Alisha Lakhani
Funding Agency and Grant Number
Corresponding Author	Alisha Lakhani, Consultant, Medicine, Shantabaa Medical College and General Hospital, Civil Hospital Campus, Lathi Road, Amreli 365601, Gujarāt, India. alishalakhani@smcgh.edu.in
Key Words	Liver fibrosis; Non-invasive test; Chronic liver diseases; Liver biopsy; Gold standard
Core Tip	Non-invasive tests are increasingly replacing liver biopsy for fibrosis assessment in chronic liver diseases due to their safety and accessibility. This systematic review highlights that elastography-based modalities provide high diagnostic accuracy for detecting significant fibrosis, while serum biomarkers serve as effective first-line screening tools. Despite variability in cut-off values and study designs, a stepwise approach combining serum and imaging-based non-invasive tests improves diagnostic reliability. Integrating these modalities into clinical practice can reduce the need for invasive procedures while maintaining accurate fibrosis staging and guiding patient management.
Citation	Shukla SR, Baig MAA, Pareek A, Johari N, Thapa Y, Kumpati BB, Nirmal SM, Ayesha Imdad I, Azid D, Aina E, Lakhani A. Accuracy of non-invasive tests for diagnosing liver fibrosis and steatosis: A systematic review. World J Gastrointest Pathophysiol 2026; In press DOI: https://doi.org/10.4291/wjgp.121790
PDF	121790-in-press.pdf

Received	2026-04-08 03:25
Peer-Review Started	2026-04-08 03:28
First Decision by Editorial Office Director	2026-04-23 05:05
Return for Revision	2026-04-23 05:05
Revised	2026-05-31 07:20
Publication Fee Transferred
Second Decision by Editor	2026-07-01 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-01 08:36
Articles in Press	2026-07-01 08:36
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5330 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com