Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	121799
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Advances in molecular mechanism of gastric cancer peritoneal metastasis
Manuscript Source	Unsolicited Manuscript
All Author List	Hai-Qing Yan, Qin-Qiao Lai, Ming-Wei Huang, Ting-An Wang, Liu-Cheng Wu and Yu-Zhou Qin
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82360593 Joint Project on Regional High-Incidence Diseases Research of Guangxi Natural Science Foundation 2023GXNSFAA026133 Guangxi Key Research and Development Program guikeAB24010097 First-Class Discipline Innovation-Driven Talent Program of Guangxi Medical University
Corresponding Author	Yu-Zhou Qin, Department of Gastrointestinal Surgery, Guangxi Medical University Cancer Hospital, Lianyu Avenue, Nanning 530021, Guangxi Zhuang Autonomous Region, China. qyz402@126.com
Key Words	Gastric cancer; Peritoneal metastasis; Mutation; Epithelial-mesenchymal transition; Extracellular matrix remodeling; Tumor microenvironment; Hypoxia; Anoikis resistance; Metabolic reprogramming; Epigenetics
Core Tip	Gastric cancer peritoneal metastasis (GCPM) involves multiple complex biological processes. These include genetic mutations, epithelial-mesenchymal transition (EMT), extracellular matrix (ECM) remodeling, tumor microenvironment (TME) interactions, hypoxia-driven responses, anoikis resistance, metabolic reprogramming, and epigenetic regulation. This review systematically elucidates the synergistic interactions among these networks. It also highlights their potential as diagnostic biomarkers and therapeutic targets.
Citation	Yan HQ, Lai QQ, Huang MW, Wang TA, Wu LC, Qin YZ. Advances in molecular mechanism of gastric cancer peritoneal metastasis. World J Gastrointest Oncol 2026; In press

Received	2026-04-02 01:02
Peer-Review Started	2026-04-02 01:03
First Decision by Editorial Office Director	2026-04-08 08:07
Return for Revision	2026-04-08 08:07
Revised	2026-04-17 13:55
Publication Fee Transferred	2026-04-23 10:37
Second Decision by Editor	2026-05-25 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-25 07:40
Articles in Press	2026-05-25 07:40
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com