BPG is committed to discovery and dissemination of knowledge
Articles in Press
5/28/2026 11:03:03 AM | Browse: 1 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
PARVA promotes gastric cancer progression through FBXO15-related PI3K/AKT signaling
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xu Lu, Jing Li, Ming-Liang Wang, Hui-Zhen Wang and Yong-Xiang Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the University Fund Project of Anhui Medical University |
2023xkj093 |
|
| Corresponding Author |
Yong-Xiang Li, Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei 230022, Anhui Province, China. liyongxiang@ahmu.edu.cn |
| Key Words |
Gastric cancer; PARVA; FBXO15; PI3K/AKT; Proliferation; Migration; Invasion |
| Core Tip |
PARVA was identified from previous proteomic screening and validated in gastric cancer. PARVA was upregulated in tumor tissues and cell lines, and high expression was associated with shorter overall survival. Functional assays showed that PARVA promoted proliferation, migration, invasion, and xenograft growth. Mechanistically, PARVA was associated with FBXO15 and activation of the PI3K/AKT pathway. These findings support PARVA as a candidate biomarker and potential therapeutic target requiring further validation. |
| Citation |
Lu X, Li J, Wang ML, Wang HZ, Li YX. PARVA promotes gastric cancer progression through FBXO15-related PI3K/AKT signaling. World J Gastrointest Oncol 2026; In press |
 |
Received |
|
2026-04-02 01:39 |
|
Peer-Review Started |
|
2026-04-02 01:40 |
|
First Decision by Editorial Office Director |
|
2026-04-28 02:36 |
|
Return for Revision |
|
2026-04-28 04:32 |
|
Revised |
|
2026-05-08 11:20 |
|
Publication Fee Transferred |
|
2026-05-09 12:36 |
|
Second Decision by Editor |
|
2026-05-28 02:35 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-05-28 11:03 |
|
Articles in Press |
|
2026-05-28 11:03 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
|
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
