Publication Name	World Journal of Translational Medicine
Manuscript ID	121879
Country	Greece

Category	Respiratory System
Manuscript Type	Minireviews
Article Title	Antiplatelet therapy in pulmonary embolism: Mechanisms and evidence
Manuscript Source	Invited Manuscript
All Author List	Tsampika-Vasileia Kalamara, Konstantinos Dodos and Vasiliki E Georgakopoulou
Funding Agency and Grant Number
Corresponding Author	Vasiliki E Georgakopoulou, Department of Pathophysiology, Laiko General Hospital, Medical School of National and Kapodistrian University of Athens, 17 Agiou Toma Street, Athens 11527, Greece. vaso_georgakopoulou@hotmail.com
Key Words	Pulmonary embolism; Platelets; Platelet aggregation inhibitors; Anticoagulation; Endothelial dysfunction
Core Tip	Although pulmonary embolism (PE) is classically considered a fibrin-rich, anticoagulation-responsive disorder, platelets are increasingly recognized as active participants in venous thrombogenesis and thrombo-inflammatory signaling. This mini-review examines the mechanistic and clinical evidence linking platelets to PE and critically evaluates the current and potential role of antiplatelet therapy in its prevention and management.
Citation	Kalamara TV, Dodos K, Georgakopoulou VE. Antiplatelet therapy in pulmonary embolism: Mechanisms and evidence. World J Transl Med 2026; In press

Received	2026-04-03 05:41
Peer-Review Started	2026-04-13 00:33
First Decision by Editorial Office Director	2026-05-25 01:46
Return for Revision	2026-05-27 07:21
Revised	2026-07-14 15:52
Publication Fee Transferred
Second Decision by Editor	2026-08-31 03:15
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-31 08:10
Articles in Press	2026-08-31 08:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6132 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com