| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Endoscopic score predicting recurrence after foam sclerotherapy in grade I internal hemorrhoids: Development and external validation
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fei-Yu Zhang, Lei-Ming Xu, Feng-Yu Gao, Wen Wang, Wu-Lian Lin, Hao Zhang, Ke-Zhou Wang, Qing-Jing Wang, Ao-Jia Jin, Ru-Ping Yang, Chun-Ying Qu, Yi Zhang, Zheng-Hong Li, Dou Wang, Cui-Cui Shi, Tian-Ben Shen, Fei Shen, Ye Hu and Feng Shen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Discipline Peak-Climbing Plan of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine |
No. XKPF2024B400 |
| Shanghai Science and Technology Commission Innovation Ecosystem Construction Plan ‘Domestic Science and Technology Cooperation’ Project |
No. 25010702300 |
| National Natural Science Foundation of China |
No. 82472899 |
|
| Corresponding Author |
Feng Shen, Chief Physician, MD, Department of Gastroenterology and Endoscopy, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai 200092, China. shenfeng01@xinhuamed.com.cn |
| Key Words |
Grade I internal hemorrhoids; Foam sclerotherapy; Recurrence; Prediction model; Endoscopy |
| Core Tip |
In this prospective multicenter study, we developed and externally evaluated Endoscopic Hemorrhoid Recurrence Score (Endo-HRS), a weighted continuous score based on sex, number of hemorrhoids, maximum hemorrhoid diameter, and red color sign grade. The model showed good discrimination in the development and external cohorts, and a nomogram estimates individual 36-month recurrence probability. Exploratory endoscopic and histopathological findings supported biological plausibility. Endo-HRS may aid risk stratification, although prospective impact studies are required before it is used to direct surveillance or retreatment. |
| Citation |
Zhang FY, Xu LM, Gao FY, Wang W, Lin WL, Zhang H, Wang KZ, Wang QJ, Jin AJ, Yang RP, Qu CY, Zhang Y, Li ZH, Wang D, Shi CC, Shen TB, Shen F, Hu Y, Shen F. Endoscopic score predicting recurrence after foam sclerotherapy in grade I internal hemorrhoids: Development and external validation. World J Gastroenterol 2026; In press
|
| PDF |
121904-in-press.pdf
|
