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Publication Name World Journal of Clinical Pediatrics
Manuscript ID 121910
Country India
Category Pediatrics
Manuscript Type Meta-Analysis
Article Title Etiological spectrum of acute encephalitis syndrome in children in India: A systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Prateek Kumar Panda, Pragnya Panda, Indar Kumar Sharawat, Dibya Prasanna Rana, Arnav Ranjan, Siddhant Govekar, Harikrishnan Kodamana, Deepak Kumar and Kalpana Panda
Funding Agency and Grant Number
Corresponding Author Kalpana Panda, Associate Professor, Department of Pediatrics, Institute of Medical Sciences and SUM Hospital, Kalinga Nagar, Bhubaneshwar 751003, Odisha, India. drkalpanapanda@gmail.com
Key Words Encephalitis; Japanese encephalitis; Scrub typhus; Dengue; Pediatrics
Core Tip This meta-analysis of 69 studies shows that scrub typhus and Japanese encephalitis are the leading identifiable etiologies of pediatric acute encephalitis syndrome (AES) in India. Enterovirus, dengue virus, herpes simplex virus, and Epstein-Barr virus are other etiological agents detected in the AES cases. These findings underline the need to consider a wider range of infectious etiologies in children presenting with AES. Broader diagnostic methods, including molecular techniques, may improve diagnostic yield and facilitate early targeted therapy in children with AES.
Citation Panda PK, Panda P, Sharawat IK, Rana DP, Ranjan A, Govekar S, Kodamana H, Kumar D, Panda K. Etiological spectrum of acute encephalitis syndrome in children in India: A systematic review and meta-analysis. World J Clin Pediatr 2026; In press
Received
2026-04-07 07:26
Peer-Review Started
2026-04-07 07:28
First Decision by Editorial Office Director
2026-04-17 08:15
Return for Revision
2026-04-17 08:15
Revised
2026-05-12 08:58
Publication Fee Transferred
Second Decision by Editor
2026-06-01 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-01 08:22
Articles in Press
2026-06-01 08:22
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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