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Publication Name World Journal of Meta-Analysis
Manuscript ID 121913
DOI 10.13105/wjma.121913
Country United Kingdom
Category Surgery
Manuscript Type Meta-Analysis
Article Title Single-step laparoscopic surgery reduces postoperative morbidity in the management of gallstones
Manuscript Source Invited Manuscript
All Author List Wajeeh Ullah Mahmood, Omar Lubbad, Omar Hamed, Shehram Shafique, Goldie Khera, Krishna K Singh and Muhammad Shafique Sajid
Funding Agency and Grant Number
Corresponding Author Wajeeh Ullah Mahmood, MD, Medical School, Brighton and Sussex Medical School, Brighton and Sussex Medical School, 94 N – S Rd, Falmer, BN19PX, Brighton BN19PX, Brighton and Hove, United Kingdom. w.mahmood1@uni.bsms.ac.uk
Key Words Cholecystocholedocholithiasis; Laparoscopic-endoscopic rendezvous; Endoscopic retrograde cholangiopancreatography; Laparoscopic cholecystectomy; Common bile duct stones; Meta-analysis
Core Tip Cholecystocholedocholithiasis is conventionally managed by two-step endoscopic retrograde cholangiopancreatography followed by laparoscopic cholecystectomy. Laparoscopic-endoscopic rendezvous (LERV) offers a single-stage alternative. This meta-analysis of six randomised controlled trials (952 patients) demonstrates that LERV significantly reduces hospital stay and overall morbidity compared with the two-step strategy, without compromising common bile duct stone clearance or increasing post-procedure pancreatitis. These findings support wider adoption of LERV in centres with appropriate expertise.
Citation Mahmood WU, Lubbad O, Hamed O, Shafique S, Khera G, Singh KK, Sajid MS. Single-step laparoscopic surgery reduces postoperative morbidity in the management of gallstones. World J Meta-Anal 2026; In press
PDF 121913-in-press.pdf
Received
2026-04-07 07:27
Peer-Review Started
2026-04-07 07:28
First Decision by Editorial Office Director
2026-04-29 01:13
Return for Revision
2026-05-01 16:35
Revised
2026-05-17 19:35
Publication Fee Transferred
Second Decision by Editor
2026-06-10 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-10 06:02
Articles in Press
2026-06-10 06:02
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2308-3840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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