Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	121975
DOI	10.4251/wjgo.121975
Country	Türkiye

Category	Surgery
Manuscript Type	Minireviews
Article Title	Multitask learning in hepatocellular carcinoma: Integrating diagnosis, prognosis, and clinical decision support
Manuscript Source	Invited Manuscript
All Author List	Sami Akbulut and Cemil Colak
Funding Agency and Grant Number
Corresponding Author	Sami Akbulut, FACS, MD, PhD, Professor, Surgery and Liver Transplantation, Inonu University Faculty of Medicine, Elazig Yolu 10 Kilometers, Malatya 44280, Türkiye. akbulutsami@gmail.com
Key Words	Hepatocellular carcinoma; Multitask learning; Deep learning; Medical imaging; Prognosis; Clinical decision support
Core Tip	Hepatocellular carcinoma (HCC) management involves interrelated tasks, including diagnosis, tumor characterization, microvascular invasion prediction, recurrence-risk estimation, survival modeling, and treatment-response assessment. Conventional single-task artificial intelligence models address these endpoints separately, limiting their ability to capture shared disease biology. This review highlights multitask learning (MTL) as an emerging integrated framework for HCC analysis. Current evidence suggests that MTL may improve performance across structurally and clinically linked tasks while providing more coherent decision support. We also summarize key architectural trends, current limitations, and future directions required for broader clinical translation of MTL in HCC through prospective validation and multicenter methodological refinement.
Citation	Akbulut S, Colak C. Multitask learning in hepatocellular carcinoma: Integrating diagnosis, prognosis, and clinical decision support. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.121975
PDF	121975-in-press.pdf

Received	2026-04-07 07:01
Peer-Review Started	2026-04-07 07:03
First Decision by Editorial Office Director	2026-04-23 03:13
Return for Revision	2026-04-23 03:13
Revised	2026-05-20 12:40
Publication Fee Transferred
Second Decision by Editor	2026-06-17 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-17 06:21
Articles in Press	2026-06-17 06:21
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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