Publication Name	World Journal of Psychiatry
Manuscript ID	121996
DOI	10.5498/wjp.121996
Country	China

Category	Psychology
Manuscript Type	Retrospective Cohort Study
Article Title	Prognostic factors analysis of depression and anxiety in infertile women with cesarean scar defects
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Bin Lin, Li-Li Luo, Ying-Xing Chen, Yu-Ping Li, Hui-Min You, Xiao-Fen Chen, Qiu-Ping Wei, Qiao-Yu Zhang and Xiao-Lan Huang
Funding Agency and Grant Number
Corresponding Author	Xiao-Lan Huang, Department of Gynecology, Army 73rd Group Military Hospital, No. 92-96 Wenyuan Road, Siming District, Xiamen 361000, Fujian Province, China. huangxiaolana@163.com
Key Words	Cesarean scar defect; Uterine niche; Depression; Anxiety; Infertility; Assisted reproductive technology; Prognostic factors; Fertility Quality of Life scale; Residual myometrial thickness
Core Tip	This retrospective cohort study is the first to systematically characterize the psychological burden of cesarean scar defect (CSD)-associated infertility and quantify its independent prognostic contribution to assisted reproductive technology (ART) outcomes. Among 100 women, clinically significant anxiety and depression were detected in 74% and 68% respectively-nearly double rates seen in general infertile populations. Multivariate logistic regression identified six independent prognostic factors for ART failure: Anxiety score, fertility-related quality of life, residual myometrial thickness, CSD severity, co-morbid anxiety and depression, and spousal support. These findings support routine psychological screening and CSD-severity-based risk stratification as essential components of ART management.
Citation	Lin XB, Luo LL, Chen YX, Li YP, You HM, Chen XF, Wei QP, Zhang QY, Huang XL. Prognostic factors analysis of depression and anxiety in infertile women with cesarean scar defects. World J Psychiatry 2026; In press DOI: https://doi.org/10.5498/wjp.121996
PDF	121996-in-press.pdf

Received	2026-05-15 10:23
Peer-Review Started	2026-05-15 10:24
First Decision by Editorial Office Director	2026-06-09 05:58
Return for Revision	2026-06-09 05:58
Revised	2026-06-15 09:52
Publication Fee Transferred
Second Decision by Editor	2026-08-06 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-10 10:15
Articles in Press	2026-08-10 10:15
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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