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Publication Name World Journal of Clinical Oncology
Manuscript ID 122037
Country Singapore
Category Oncology
Manuscript Type Minireviews
Article Title Metastasis to the adrenal glands: An update
Manuscript Source Invited Manuscript
All Author List Jing-Rong Yu, Tee Hui Maxim Tan, Anil D Rao, Sunder Balasubramaniam and Vishal G Shelat
Funding Agency and Grant Number
Corresponding Author Vishal G Shelat, Adjunct Associate Professor, FRCS, Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore, Singapore. vgshelat@gmail.com
Key Words Adrenal gland; Adrenalectomy; Metastases; Percutaneous ablation; Stereotactic body radiotherapy
Core Tip Adrenal metastasis is increasingly identified during staging and surveillance, but outcomes vary widely by primary tumor biology, rate of progression, and whether disease is truly isolated. Management should follow an intent-based pathway: Confirm diagnosis with high-quality imaging, reserve biopsy for indeterminate lesions when results will change treatment and select local therapy accordingly. For carefully chosen patients, adrenalectomy offers durable control; percutaneous ablation and stereotactic body radiotherapy provide effective, lower-morbidity alternatives for non-operative candidates or anatomically challenging lesions. Standardized selection criteria and stratified reporting are essential to define when local treatment meaningfully changes trajectory.
Citation Yu JR, Tan THM, Rao AD, Balasubramaniam S, Shelat VG. Metastasis to the adrenal glands: An update. World J Clin Oncol 2026; In press
Received
2026-04-16 02:21
Peer-Review Started
2026-04-16 02:22
First Decision by Editorial Office Director
Return for Revision
2026-06-25 03:15
Revised
2026-07-05 11:49
Publication Fee Transferred
Second Decision by Editor
2026-07-08 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-08 03:22
Articles in Press
2026-07-08 03:22
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2218-4333 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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