Publication Name	World Journal of Psychiatry
Manuscript ID	122042
DOI	10.5498/wjp.122042
Country	China

Category	Psychology
Manuscript Type	Observational Study
Article Title	Determinants of psychological emotions in lung cancer patients and their correlations with tumor markers and inflammatory cytokines
Manuscript Source	Unsolicited Manuscript
All Author List	Peng Wu, Jun Chen, Jie Ding, Feng Shi, Hua Wu and Jun Yang
Funding Agency and Grant Number	Funding Agency Grant Number Henan Provincial Science and Technology Research Project 242102310491 Henan Provincial Higher Education Key Scientific Research Project Plan 25B320029 Xinyang Municipal Science and Technology Research Project 20250083
Corresponding Author	Peng Wu, Lecturer, School of Medical Laboratory Technology, Xinyang Vocational and Technical College, No. 48 24th Street, Yangshan New District, Xinyang 464000, Henan Province, China. victorwumed@163.com
Key Words	Lung cancer; Anxiety; Depression; Tumor markers; Inflammatory cytokines
Core Tip	This study assessed the prevalence of anxiety and depression, alongside associated psychosocial factors, in 128 patients with stage C advanced non-small cell lung cancer undergoing chemoradiotherapy. Additionally, it examined the cross-sectional relationships between these factors and serum tumor markers and pro-inflammatory cytokines. The findings demonstrate a significant correlation between psychological distress and socioeconomic factors; notably, elevated levels of emotional distress are linked to higher biomarker concentrations. This study highlights potential psychoneuroimmunological pathways involved in lung cancer progression and emphasizes the importance of integrating mental health screening into cancer treatment to enhance patients’ physical and mental well-being and improve biological outcomes.
Citation	Wu P, Chen J, Ding J, Shi F, Wu H, Yang J. Determinants of psychological emotions in lung cancer patients and their correlations with tumor markers and inflammatory cytokines. World J Psychiatry 2026; In press DOI: https://doi.org/10.5498/wjp.122042
PDF	122042-in-press.pdf

Received	2026-04-30 09:26
Peer-Review Started	2026-04-30 09:26
First Decision by Editorial Office Director	2026-05-25 03:32
Return for Revision	2026-05-25 03:32
Revised	2026-06-28 15:33
Publication Fee Transferred
Second Decision by Editor	2026-07-27 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-28 13:02
Articles in Press	2026-07-28 13:02
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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