Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	122122
DOI	10.5409/wjcp.122122
Country	Thailand

Category	Gastroenterology & Hepatology
Manuscript Type	Clinical Trials Study
Article Title	Impact of Limosilactobacillus reuteri DSM 17938 on early-life gut microbial diversity
Manuscript Source	Invited Manuscript
All Author List	Tanawan Noicharoen, Duc Long Tran, Areewan Soontornsook, Chonnikant Visuthranukul, Thanita Thammarakcharoen, Pavit Klomkliew, Suthida Visedthorn, Kittima Phutthawong, Sunchai Payungporn and Palittiya Sintusek
Funding Agency and Grant Number	Funding Agency Grant Number Ratchadapiseksompotch Fund No. 67/026 Ratchadapiseksompotch Fund No. 67/027 Thailand Science research and Innovation Fund Chulalongkorn University No. HEA_FF_69_225_3000_031 the Second Century Fund (C2F) from Chulalongkorn University
Corresponding Author	Palittiya Sintusek, Associate Professor, MD, PhD, Center of Excellence in Thai Pediatric Gastroenterology, Hepatology and Immunology (TPGHAI), Division of Gastroenterology and Hepatology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, 1873 Rama IV, Pathumwan, Bangkok 10330, Thailand. palittiya.s@chula.ac.th
Key Words	Gut microbiota; Limosilactobacillus reuteri DSM 17938; Probiotics; Infant; Functional gastrointestinal disorder
Core Tip	While Limosilactobacillus reuteri (L. reuteri) DSM 17938 has demonstrated benefits in several pediatric gastrointestinal conditions, its effects on gut microbiota modulation in exclusively breastfed infants remain unclear. In this prospective sub-study of a randomized controlled trial, L. reuteri DSM 17938 supplementation during the first two months of life was associated with an increased Bifidobacterium abundance and, independently of the delivery modes, higher Parabacteroides and Hungatella hathewayi were the most distinctive species identified in vaginally- and cesarean-delivered infants, respectively. L. reuteri DSM 17938 administration induced only modest and transient microbiota changes, with no evidence of sustained colonization.
Citation	Noicharoen T, Tran DL, Soontornsook A, Thammarakcharoen T, Klomkliew P, Visedthorn S, Phutthawong K, Visuthranukul C, Payungporn S, Sintusek P. Impact of Limosilactobacillus reuteri DSM 17938 on early-life gut microbial diversity. World J Clin Pediatr 2026; In press DOI: https://doi.org/10.5409/wjcp.122122
PDF	122122-in-press.pdf

Received	2026-04-10 03:23
Peer-Review Started	2026-04-10 03:25
First Decision by Editorial Office Director	2026-05-29 09:11
Return for Revision	2026-05-29 09:11
Revised	2026-06-01 09:33
Publication Fee Transferred
Second Decision by Editor	2026-06-17 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-17 03:20
Articles in Press	2026-06-17 03:20
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2808 (online)
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