Publication Name	World Journal of Gastroenterology
Manuscript ID	122272
Country	Germany

Category	Surgery
Manuscript Type	Retrospective Cohort Study
Article Title	Role of postoperative endoscopy after peroral endoscopic myotomy: Evidence from a large cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Carolin Kastner, Malika Aktanova, Lars Kollmann, Alexandra Marschalek, Friederike Meyer, Jana Anger, Ilona Flemming, Jakob Lauerer, Alexander Weich, Markus Brand, Alexander Hann, Burkard HA von Rahden, Sven Flemming, Christoph-Thomas Germer and Florian Seyfried
Funding Agency and Grant Number
Corresponding Author	Florian Seyfried, Department of General, Visceral, Transplantation, Vascular, and Pediatric Surgery, University Hospital Wuerzburg, Oberdürrbacherstraße 6, Wuerzburg 97080, Germany. seyfried_f@ukw.de
Key Words	Achalasia; Peroral endoscopic myotomy; Adverse events; Postoperative endoscopy; Perioperative care
Core Tip	Although peroral endoscopic myotomy (POEM) is an established treatment for achalasia, evidence guiding optimal perioperative management remains limited. In this large single-center cohort of 417 patients, we identified independent risk factors for intraoperative adverse events and pathological findings in postoperative endoscopy following POEM. Risk stratification based on these factors substantially reduced the number needed to screen for clinically relevant endoscopic findings requiring intervention. These data provide evidence-based guidance for individualized perioperative management after POEM and support a selective, risk-adapted postoperative endoscopic strategy that preserves patient safety while reducing unnecessary procedures.
Citation	Kastner C, Aktanova M, Kollmann L, Marschalek A, Meyer F, Anger J, Flemming I, Lauerer J, Weich A, Brand M, Hann A, von Rahden BHA, Flemming S, Germer CT, Seyfried F. Role of postoperative endoscopy after peroral endoscopic myotomy: Evidence from a large cohort study. World J Gastroenterol 2026; In press

Received	2026-04-14 01:26
Peer-Review Started	2026-04-14 01:35
First Decision by Editorial Office Director	2026-05-19 06:04
Return for Revision	2026-05-19 06:04
Revised	2026-06-05 21:11
Publication Fee Transferred
Second Decision by Editor	2026-07-03 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-03 07:28
Articles in Press	2026-07-03 07:28
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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