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Articles in Press
7/1/2026 3:30:18 AM | Browse: 2 | Download: 0
| Category |
Psychology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Comprehensive psychological and neurological rehabilitation for post-stroke depression: A retrospective comparative study with biomarker exploration
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shan-Zhong Yan, Zeng-Yan Hu, Hong-Ying Zhou and Song Chai |
| Funding Agency and Grant Number |
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| Corresponding Author |
Song Chai, Consultant, Lecturer, Department of Rehabilitation Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Hongkou District, Shanghai 200080, China. 15800452862@163.com |
| Key Words |
Post-stroke depression; Psychological rehabilitation; Cognitive behavioral therapy; Neuropeptide Y; Neurological rehabilitation; Neuroinflammation; Nomogram prediction model |
| Core Tip |
Ischemic stroke can lead to post-stroke depression (PSD), which is an important protective factor for neurological recovery, rehabilitation compliance and patient quality of life. In this retrospective study, we found that a cognitive behavioral therapy-centered comprehensive rehabilitation program integrating psychological with neurological rehabilitation was superior to standard care in terms of depressive symptoms, motor recovery, cognitive function and daily living ability. Baseline serum neuropeptide Y identified as a prospective treatment response biomarker. Earlier intervention, enhanced family engagement, preserved cognition, reduced inflammation and non-dominant hemisphere lesions also predicted better outcomes. An internally validated nomogram might facilitate individualized rehabilitation planning in PSD patients. |
| Citation |
Yan SZ, Hu ZY, Zhou HY, Chai S. Comprehensive psychological and neurological rehabilitation for post-stroke depression: A retrospective comparative study with biomarker exploration. World J Psychiatry 2026; In press
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Received |
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2026-05-09 10:53 |
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Peer-Review Started |
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2026-05-09 10:53 |
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First Decision by Editorial Office Director |
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2026-05-29 03:41 |
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Return for Revision |
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2026-05-29 03:41 |
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Revised |
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2026-06-24 11:04 |
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Publication Fee Transferred |
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2026-06-26 13:54 |
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Second Decision by Editor |
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2026-07-01 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-01 03:30 |
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Articles in Press |
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2026-07-01 03:30 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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