Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	122446
DOI	10.4240/wjgs.122446
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Perianal Paget’s disease with concomitant rectal cancer: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Kai Lv, Long-Zhan Dong, Hui Yang, Yu-Lin Liu, Han Li, Ke-Liang Jia, Xian-Hai Zhao and Jing-Bo Chen
Funding Agency and Grant Number
Corresponding Author	Jing-Bo Chen, Director, Full Professor, PhD, Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, No. 16766 Jingshi Road, Jinan 250014, Shandong Province, China. qychenjingbo@163.com
Key Words	Perianal Paget’s disease; Rectal cancer; Adenocarcinoma; Abdominoperineal resection; Case report
Core Tip	Perianal Paget’s disease is rare and may mimic benign perianal disorders, resulting in delayed diagnosis. This case highlights the need for biopsy of persistent perianal ulceration and complete anorectal evaluation. The resected specimen confirmed rectal adenocarcinoma with Paget’s disease. Immunohistochemistry showed retained mismatch repair proteins and negative BRAF expression, and molecular testing revealed no typical KRAS, NRAS, BRAF, or PIK3CA mutations.
Citation	Lv K, Dong LZ, Yang H, Liu YL, Li H, Jia KL, Zhao XH, Chen JB. Perianal Paget’s disease with concomitant rectal cancer: A case report. World J Gastrointest Surg 2026; In press DOI: https://doi.org/10.4240/wjgs.122446
PDF	122446-in-press.pdf

Received	2026-04-22 05:58
Peer-Review Started	2026-04-22 05:59
First Decision by Editorial Office Director	2026-05-20 06:30
Return for Revision	2026-05-20 06:30
Revised	2026-05-29 15:22
Publication Fee Transferred	2026-06-05 06:56
Second Decision by Editor	2026-07-09 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-09 06:18
Articles in Press	2026-07-09 06:18
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
Open Access	Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com