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Articles in Press
7/3/2026 7:16:40 AM | Browse: 5 | Download: 0
| Category |
Food Science & Technology |
| Manuscript Type |
Basic Study |
| Article Title |
Dendrobium officinale polysaccharides attenuates spasmolytic polypeptide-expressing metaplasia via dual modulation of gastric epithelial cell fate and macrophage polarization
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi Zhao, Xue-Feng Lu, Lu Liu, Hong Fang, Shuo Sun, Hong-Ning Liu and You-Zhi Sun |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82560860 |
| Jiangxi Provincial Natural Science Foundation Project |
No. 20242BAB25562 |
| National Key R&D Program of China |
No. 2024YFE0104600 |
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| Corresponding Author |
You-Zhi Sun, Professor, School of Chinese Medicine, Jiangxi University of Chinese Medicine, No. 1688 Meiling Avenue, Xinjian District, Nanchang 330004, Jiangxi Province, China. 20040792@jxutcm.edu.cn |
| Key Words |
Dendrobium officinale polysaccharides; Spasmolytic polypeptide-expressing metaplasia; M2 macrophage polarization; IL-13/STAT6 signaling pathway; Chief cells |
| Core Tip |
Dendrobium officinale polysaccharides upregulated the expression of ATP4a and GS II, while concurrently reducing the differentiation of chief cells. Furthermore, it inhibited M2 macrophage polarization via the IL-13/STAT6 signaling pathway and was identified as a protective agent against spasmolytic polypeptide-expressing metaplasia. |
| Citation |
Zhao Y, Lu XF, Liu L, Fang H, Sun S, Liu HN, Sun YZ. Dendrobium officinale polysaccharides attenuates spasmolytic polypeptide-expressing metaplasia via dual modulation of gastric epithelial cell fate and macrophage polarization. World J Gastroenterol 2026; In press
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Received |
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2026-04-21 03:47 |
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Peer-Review Started |
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2026-04-21 03:48 |
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First Decision by Editorial Office Director |
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2026-05-29 07:19 |
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Return for Revision |
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2026-05-29 07:19 |
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Revised |
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2026-06-14 14:33 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-07-03 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-03 07:16 |
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Articles in Press |
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2026-07-03 07:16 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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