Publication Name	World Journal of Translational Medicine
Manuscript ID	122602
DOI	10.5528/wjtm.122602
Country	Egypt

Category	Pediatrics
Manuscript Type	Editorial
Article Title	Beyond assumptions: Revisiting the link between consanguinity and pediatric neurodevelopmental disorders
Manuscript Source	Invited Manuscript
All Author List	Mohammed Al-Beltagi
Funding Agency and Grant Number	Funding Agency Grant Number None
Corresponding Author	Mohammed Al-Beltagi, Chairman, Consultant, Head, MD, PhD, Professor, Department of Pediatrics, Faculty of Medicine, Tanta University, 1 Hassan Radwan Street, Tanta 31511, Algharbia, Egypt. mbelrem@hotmail.com
Key Words	Consanguinity; Neurodevelopmental disorders; Epilepsy; Genetic counseling; Autosomal recessive diseases; Pediatric neurology; Gene-environment interaction; Saudi Arabia; Middle East
Core Tip	This editorial interprets a recent cohort study reporting no clear association between consanguinity and neurodevelopmental disorders by highlighting the distinction between monogenic and multifactorial conditions and the impact of cohort heterogeneity on the detectability of risk. It emphasizes the importance of risk-stratified clinical approaches, including early developmental screening and culturally sensitive genetic counseling, and calls for prospective, genomically informed research to clarify disease-specific associations.
Citation	Al-Beltagi M. Beyond assumptions: Revisiting the link between consanguinity and pediatric neurodevelopmental disorders. World J Transl Med 2026; In press DOI: https://doi.org/10.5528/wjtm.122602
PDF	122602-in-press.pdf

Received	2026-04-23 06:29
Peer-Review Started	2026-04-23 06:29
First Decision by Editorial Office Director	2026-05-22 10:10
Return for Revision	2026-05-24 16:33
Revised	2026-05-24 17:12
Publication Fee Transferred
Second Decision by Editor	2026-06-11 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-11 08:33
Articles in Press	2026-06-11 08:33
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6132 (online)
Open Access	Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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