Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	122614
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Omeprazole-cisapride combination for gastroparesis following radical gastrectomy for gastric cancer: An efficacy and safety analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Shan-Lin Zhu, Qian Gao, Yang Liu and Kun-Peng Cheng
Funding Agency and Grant Number
Corresponding Author	Kun-Peng Cheng, Associate Chief Physician, Department of Gastroenterology Medicine, Huangshi Fifth Hospital, No. 33 Xialu Dadao, Xialu District, Huangshi 435005, Hubei Province, China. 18934660891@163.com
Key Words	Omeprazole; Cisapride; Radical gastrectomy; Gastroparesis; Effect; Safety
Core Tip	This retrospective study evaluated the clinical efficacy and safety of omeprazole (OME) combined with cisapride in patients with gastroparesis following radical gastrectomy for gastric cancer. The combination regimen was more effective than OME alone without increasing the overall incidence of adverse reactions. It also demonstrated clinical advantages in promoting symptom relief, accelerating gastrointestinal function recovery, and actively regulating gastrointestinal hormones. Patients with stage IIB-III disease, baseline motilin < 309 mg/L, and treatment with OME alone were at increased risk of treatment inefficacy.
Citation	Zhu SL, Gao Q, Liu Y, Cheng KP. Omeprazole-cisapride combination for gastroparesis following radical gastrectomy for gastric cancer: An efficacy and safety analysis. World J Gastrointest Surg 2026; In press

Received	2026-06-10 11:17
Peer-Review Started	2026-06-10 11:18
First Decision by Editorial Office Director
Return for Revision	2026-06-29 01:28
Revised	2026-07-16 13:07
Publication Fee Transferred	2026-07-24 05:32
Second Decision by Editor	2026-08-26 02:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-26 08:46
Articles in Press	2026-08-26 08:46
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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