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6/29/2026 8:18:11 AM | Browse: 23 | Download: 7
Publication Name World Journal of Diabetes
Manuscript ID 122649
DOI 10.4239/wjd.122649
Country United States
Category Pediatrics
Manuscript Type Observational Study
Article Title Serum elemental profiles and their associations with glycemic control in pediatric type 1 and type 2 diabetes
Manuscript Source Invited Manuscript
All Author List Ahmed Abdelbaset-Ismail, Xiaodan Hui, Qian Lin, Chunjie Gu, Jason Xu, Sara Watson, Lu Cai, Yi Tan and Kupper A Wintergerst
Funding Agency and Grant Number
Funding Agency Grant Number
National Institutes of Health (NIH) No. X01DK125891
National Institutes of Health (NIH) No. R01HL125877
National Institutes of Health (NIH) No. P30ES030283
Jewish Heritage Fund for Excellence Research Enhancement Grant Program at the University of Louisville School of Medicine
Corresponding Author Yi Tan, Full Professor, PhD, Phoenix Children’s Research Institute, Department of Child Health, University of Arizona College of Medicine, 475 N 5th St, Phoenix, AZ 85004, United States. yitan@arizona.edu
Key Words Diabetes; Children; Adolescents; Race; Ethnicity; Zinc/copper ratio; Trace elements
Core Tip Trace elements play important roles in glucose metabolism, insulin action, and oxidative stress, yet their relationships to glycemic control in pediatric diabetes remain incompletely understood. This study comprehensively evaluated serum elemental profiles in children and adolescents with type 1 diabetes mellitus and type 2 diabetes mellitus. Distinct alterations in zinc, copper, magnesium, selenium, and trace-element ratios were identified, and several elements showed significant associations with glycated hemoglobin. These findings provide new insights into elemental dysregulation in pediatric diabetes and highlight potential biomarkers for glycemic control.
Citation Abdelbaset-Ismail A, Hui X, Lin Q, Gu C, Xu J, Watson S, Cai L, Tan Y, Wintergerst KA. Serum elemental profiles and their associations with glycemic control in pediatric type 1 and type 2 diabetes. World J Diabetes 2026; In press
PDF 122649-in-press.pdf
Received
2026-04-27 01:46
Peer-Review Started
2026-04-28 23:57
First Decision by Editorial Office Director
2026-06-01 08:04
Return for Revision
2026-06-01 08:04
Revised
2026-06-11 21:38
Publication Fee Transferred
Second Decision by Editor
2026-06-29 02:20
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-29 08:18
Articles in Press
2026-06-29 08:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9358 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com