Publication Name	World Journal of Translational Medicine
Manuscript ID	122740
DOI	10.5528/wjtm.122740
Country	Norway

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Possible roles of short-chain fatty acids in the pathophysiology and treatment of irritable bowel syndrome
Manuscript Source	Invited Manuscript
All Author List	Magdy El‐Salhy, Cheol Min Shin, Yong Sung Kim and Jan Gunnar Hatlebakk
Funding Agency and Grant Number
Corresponding Author	Magdy El‐Salhy, Chief Physician, Professor Emeritus, <named-content content-type="organisation-division">Department of Clinical Medicine</named-content><institution>University of Bergen</institution><city>Bergen</city><country country="NO">Norway</country>, <named-content content-type="organisation-division">Department of Medicine, UNIVERSITY OF BERGEN,HAUKELAND UNIVERSITY HOSPITAL, <named-content content-type="organisation-division">Department of Clinical Medicine</named-content><institution>University of Bergen</institution><city>Bergen</city><country country="NO">Norway</country>,<named-content content-type="organisation-division">Department of Medicine, National Centre for Functional Gastrointestinal Disorders</named-content><institution>Haukeland University Hospital</institution><city>Bergen</city><country country="NO">Norway</country>, Bergen 5009, Norway. magdy.el-salhy@helse-bergen.no
Key Words	Acetic acid; Butyric acid; Fatigue; Glucagon-like peptide-1; Peptide YY; Propionic acid; Serotonin
Core Tip	Butyric acid appears to play a significant role in irritable bowel syndrome (IBS) symptom manifestation and the overlapping chronic fatigue. Sodium butyrate in capsule form seems to be a promising treatment for IBS
Citation	El‐Salhy M, Shin CM, Kim YS, Hatlebakk JG. Possible roles of short-chain fatty acids in the pathophysiology and treatment of irritable bowel syndrome. World J Transl Med 2026; In press DOI: https://doi.org/10.5528/wjtm.122740
PDF	122740-in-press.pdf

Received	2026-04-27 08:46
Peer-Review Started	2026-04-27 08:47
First Decision by Editorial Office Director	2026-06-04 10:53
Return for Revision	2026-06-05 14:51
Revised	2026-06-16 21:51
Publication Fee Transferred
Second Decision by Editor	2026-08-06 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-10 10:06
Articles in Press	2026-08-10 10:06
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6132 (online)
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