Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	122768
DOI	10.4251/wjgo.122768
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Gastric amphicrine carcinoma with leptomeningeal metastases: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Chao Deng, Yan-Fen Shi, Wen-Juan Guo, Chao Wang, Dong-Mei Chen and Huang-Ying Tan
Funding Agency and Grant Number	Funding Agency Grant Number National High Level Hospital Clinical Research Funding 2025-NHLHCRF-PY-11 Elite Medical Professionals Project of China-Japan Friendship Hospital ZRJY2023-GG01 Remaining Funds of the National Natural Science Foundation of China 2026-GZRJY-02
Corresponding Author	Huang-Ying Tan, MD, PhD, Professor, Department of Integrative Oncology, China-Japan Friendship Hospital, No. 2 Yinghuayuan East Street, Chaoyang District, Beijing 100029, China. tanhuangying@zryhyy.com.cn
Key Words	Gastric carcinoma; Neuroendocrine neoplasm; Amphicrine carcinoma; Hepatic metastasis; Leptomeningeal metastasis; Case report
Core Tip	Based on histopathological findings from both the primary tumor and metastatic site, this case was diagnosed as advanced gastric amphicrine carcinoma. The patient underwent multiple lines of therapy, along with serial imaging and endoscopic evaluations. Nevertheless, the tumor did not respond well to treatment regimens typically used for conventional adenocarcinoma. In the end, the patient died from a rare leptomeningeal metastasis, indicating an unfavorable prognosis.
Citation	Deng C, Shi YF, Guo WJ, Wang C, Chen DM, Tan HY. Gastric amphicrine carcinoma with leptomeningeal metastases: A case report. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.122768
PDF	122768-in-press.pdf

Received	2026-04-28 01:34
Peer-Review Started	2026-04-28 01:34
First Decision by Editorial Office Director	2026-05-13 02:27
Return for Revision	2026-05-14 05:10
Revised	2026-06-04 08:49
Publication Fee Transferred	2026-06-08 05:40
Second Decision by Editor	2026-06-22 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-22 08:41
Articles in Press	2026-06-22 08:41
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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