Publication Name	World Journal of Diabetes
Manuscript ID	122779
DOI	10.4239/wjd.122779
Country	South Korea

Category	Endocrinology & Metabolism
Manuscript Type	Retrospective Cohort Study
Article Title	Peripheral arterial disease is associated with retinal fluid and microvascular alterations in type 2 diabetes
Manuscript Source	Unsolicited Manuscript
All Author List	Jee Myung Yang, Jiehoon Kwak, Se Hee Min, Sang Uk Choi, Jaeyu Park, Dong Keon Yon, Joo Yong Lee, June-Gone Kim, Young Hee Yoon and Yoon Jeon Kim
Funding Agency and Grant Number	Funding Agency Grant Number Korea Drug Development Fund RS-2023-00283544, RS-2024-00405141 Korean ARPA-H Project through the Korea Health Industry Development Institute RS-2025-25455885 National Research Foundation of Korea RS-202400441114 Korean Retina Foundation, 2024 Fund
Corresponding Author	Yoon Jeon Kim, Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, South Korea. yjkim@amc.seoul.kr
Key Words	Peripheral arterial disease; Type 2 diabetes mellitus; Retinal microvasculature; Intraretinal fluid; Optical coherence tomography angiography
Core Tip	Peripheral arterial disease in type 2 diabetes was associated with lower superficial and deep capillary plexus vessel density on optical coherence tomography angiography and with substantially higher risk of intraretinal fluid and diabetic macular edema. The association persisted under a skeptical Bayesian prior and inverse probability weighting, and one-third of the PAD-intraretinal fluid association was mediated through deep capillary plexus vessel density. These findings support retinal risk stratification for patients with diabetes and coexisting macrovascular disease.
Citation	Yang JM, Kwak J, Min SH, Choi SU, Park J, Yon DK, Lee JY, Kim JG, Yoon YH, Kim YJ. Peripheral arterial disease is associated with retinal fluid and microvascular alterations in type 2 diabetes. World J Diabetes 2026; In press DOI: https://doi.org/10.4239/wjd.122779
PDF	122779-in-press.pdf

Received	2026-04-30 00:35
Peer-Review Started	2026-05-08 09:00
First Decision by Editorial Office Director	2026-06-01 02:58
Return for Revision	2026-06-01 02:58
Revised	2026-06-12 01:56
Publication Fee Transferred	2026-06-18 02:40
Second Decision by Editor	2026-07-09 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-28 13:03
Articles in Press	2026-07-28 13:03
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com