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Publication Name World Journal of Clinical Pediatrics
Manuscript ID 122880
DOI 10.5409/wjcp.122880
Country India
Category Allergy
Manuscript Type Retrospective Cohort Study
Article Title Clinical and functional correlates of blood eosinophilia in pediatric asthma: A retrospective cohort study
Manuscript Source Invited Manuscript
All Author List Rashmi Ranjan Das, Manoj Kumar Panigrahi, Samarendra Mahapatro and Joseph John
Funding Agency and Grant Number
Corresponding Author Rashmi Ranjan Das, FCCP, MD, Professor, Department of Pediatrics, All India Institute of Medical Sciences, Sijua, Patrapada, Bhubaneswar 751019, Odisha, India. ped_rashmi@aiimsbhubaneswar.edu.in
Key Words Pediatric asthma; Blood eosinophilia; Biomarker; Type 2 inflammation; Asthma control
Core Tip Asthma with blood eosinophilia (driven by type 2 inflammation) is associated with increased asthma severity and poor asthma control. In this retrospective cohort study, we included 176 children with asthma, of which 84 had eosinophilic asthma. Asthma with blood eosinophilia (asthma with an absolute eosinophil count of ≥ 400 cells/mm³) was associated with poor asthma control, greater disease severity, and increased airflow limitation. Peripheral eosinophil count may serve as a practical biomarker for risk stratification and personalized asthma management in a low-and-middle-income country setting.
Citation Das RR, Panigrahi MK, Mahapatro S, John J. Clinical and functional correlates of blood eosinophilia in pediatric asthma: A retrospective cohort study. World J Clin Pediatr 2026; In press
PDF 122880-in-press.pdf
Received
2026-05-07 07:47
Peer-Review Started
2026-05-07 07:47
First Decision by Editorial Office Director
2026-06-02 13:24
Return for Revision
2026-06-02 13:24
Revised
2026-06-13 19:27
Publication Fee Transferred
Second Decision by Editor
2026-06-26 02:16
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-26 07:07
Articles in Press
2026-06-26 07:07
Edit the Manuscript by Language Editor
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ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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