Publication Name	World Journal of Clinical Cases
Manuscript ID	122937
DOI	10.12998/wjcc.122937
Country	Türkiye

Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	Oxidative stress and inflammation in breast cancer: Mechanistic interactions and clinical implications
Manuscript Source	Invited Manuscript
All Author List	Seyma Tutar, Kezban Uçar Çifçi and Yusuf Tutar
Funding Agency and Grant Number
Corresponding Author	Yusuf Tutar, Chairman, Dean, Tenured Professor, Division of Medicinal Biochemistry, Department of Basic Medical Sciences, Recep Tayyip Erdogan University, Islampaşa, Rize 53020, Türkiye. yusuf.tutar@erdogan.edu.tr
Key Words	Breast cancer; Oxidative stress; Inflammation; Tumor microenvironment; Triple-negative breast cancer; Biomarkers
Core Tip	This review integrates contemporary findings regarding the bidirectional interaction between oxidative stress and inflammation in breast cancer, emphasizing common signaling pathways that facilitate tumor initiation, development, and treatment resistance. This work examines how reactive oxygen species alter the tumor microenvironment, drive genetic instability, and sustain inflammation, while inflammatory mediators exacerbate oxidative damage. Further, it assesses novel biomarkers and tailored therapies that leverage this interaction, providing insights into individualized therapeutic approaches and prospective tactics to improve treatment efficacy and address resistance.
Citation	Tutar Ş, Uçar Çifçi K, Tutar Y. Oxidative stress and inflammation in breast cancer: Mechanistic interactions and clinical implications. World J Clin Cases 2026; In press DOI: https://doi.org/10.12998/wjcc.122937
PDF	122937-in-press.pdf

Received	2026-05-11 06:01
Peer-Review Started	2026-05-11 06:02
First Decision by Editorial Office Director	2026-06-04 11:22
Return for Revision	2026-06-04 11:22
Revised	2026-06-18 18:32
Publication Fee Transferred
Second Decision by Editor	2026-07-27 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-28 12:59
Articles in Press	2026-07-28 12:59
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
Open Access	Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com