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Publication Name World Journal of Clinical Oncology
Manuscript ID 122944
Country China
Category Surgery
Manuscript Type Retrospective Cohort Study
Article Title Comprehensive prognostic value of prealbumin and albumin in hepatocellular carcinoma resection: Insights from a Chinese multicenter cohort
Manuscript Source Unsolicited Manuscript
All Author List Hao-Xin Shen, Yin-Sen Song, Hui-Feng Wang, Chen Chen, Jin-Kun Song, Chen-Guang Sun, Shu-Zhai Miao, Xin-Guo Chen, Shi-Lei Bai, Yun-Feng Zhao and Kui Wang
Funding Agency and Grant Number
Corresponding Author Kui Wang, Academic Fellow, Chief Physician, Full Professor, Department of Hepatic Surgery II, Eastern Hepatobiliary Surgery Hospital, Department of Hepatic Surgery II, the Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China. Electronic address: wangkuiykl@163.com., Shanghai 200433, China. wangkuiykl@163.com
Key Words Prealbumin; Hepatocellular carcinoma; Hepatectomy; Overall survival; Recurrence-free survival
Core Tip In this multicenter Chinese cohort of 1550 hepatocellular carcinoma patients undergoing curative resection, prealbumin demonstrated superior prognostic value over albumin for overall survival and recurrence free survival. When both markers were combined, low prealbumin with normal or low albumin independently predicted worse outcomes, whereas isolated low albumin did not. This dual marker approach enables precise risk stratification to guide surgical decisions and postoperative management.
Citation Shen HX, Song YS, Wang HF, Chen C, Song JK, Sun CG, Miao SZ, Chen XG, Bai SL, Zhao YF, Wang K. Comprehensive prognostic value of prealbumin and albumin in hepatocellular carcinoma resection: Insights from a Chinese multicenter cohort. World J Clin Oncol 2026; In press
Received
2026-05-07 01:42
Peer-Review Started
2026-05-07 01:42
First Decision by Editorial Office Director
Return for Revision
2026-07-14 13:08
Revised
2026-08-12 15:08
Publication Fee Transferred
2026-09-19 11:59
Second Decision by Editor
2026-10-10 03:25
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-10 09:10
Articles in Press
2026-10-10 09:10
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2218-4333 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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