Publication Name	World Journal of Gastroenterology
Manuscript ID	122970
DOI	10.3748/wjg.122970
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Pancreatic adenocarcinoma complicated by intramural duodenal hematoma: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Hugh Shunsuke Colvin, Masaki Wato, Ichiro Sakakihara, Kosei Akashi, Kunio Okamoto, Kenta Sui, Satoko Nakamura and Tomoki Inaba
Funding Agency and Grant Number
Corresponding Author	Hugh Shunsuke Colvin, Consultant, Department of Gastroenterology, Kagawa Prefectural Central Hospital, 1-2-1 Asahimachi, Takamatsu 760-8557, Kagawa, Japan. hughshunsukecolvin@gmail.com
Key Words	Intramural duodenal hematoma; Pancreatic cancer; Pancreaticoduodenectomy; Neoadjuvant chemotherapy; Natural history; Review of the literature; Case report
Core Tip	Intramural duodenal hematoma in patients with pancreatic cancer is exceedingly rare. We report the first case in which the natural history of intramural duodenal hematoma associated with pancreatic cancer was observed beyond the early phase following initial presentation. In this case, the patient ultimately underwent pancreaticoduodenectomy after rebleeding of the hematoma increased the risk of further hemorrhage, which could have compromised the safe administration of neoadjuvant chemotherapy. In similar cases of resectable pancreatic cancer complicated by intramural duodenal hematoma, up-front surgery should be considered in light of the risk of rebleeding and the limited evidence supporting neoadjuvant therapy.
Citation	Colvin HS, Wato M, Sakakihara I, Akashi K, Okamoto K, Sui K, Nakamura S, Inaba T. Pancreatic adenocarcinoma complicated by intramural duodenal hematoma: A case report and review of literature. World J Gastroenterol 2026; In press DOI: https://doi.org/10.3748/wjg.122970
PDF	122970-in-press.pdf

Received	2026-05-06 02:21
Peer-Review Started	2026-05-06 02:22
First Decision by Editorial Office Director	2026-05-29 08:15
Return for Revision	2026-05-29 08:15
Revised	2026-06-11 13:43
Publication Fee Transferred	2026-06-30 13:51
Second Decision by Editor	2026-07-13 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-13 08:28
Articles in Press	2026-07-13 08:28
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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