Publication Name	World Journal of Clinical Cases
Manuscript ID	123160
DOI	10.12998/wjcc.123160
Country	India

Category	Dentistry, Oral Surgery & Medicine
Manuscript Type	Minireviews
Article Title	Salivary thioredoxin-1 as a non-invasive redox biomarker in oral diseases
Manuscript Source	Invited Manuscript
All Author List	Sivan Sathish, Ankita Jain, Haritma Nigam, Vikas Singh and Upender Malik
Funding Agency and Grant Number
Corresponding Author	Sivan Sathish, Head, Professor, Department of Oral Medicine and Radiology, Teerthanker Mahaveer Dental College and Research Centre, Teerthanker Mahaveer University, Delhi Road, Moradabad 244001, Uttar Pradesh, India. drsivan.dental@tmu.ac.in
Key Words	Oral disease; Oxidative stress; Redox marker; Salivary biomarker; Thioredoxin-1
Core Tip	Redox imbalance is an important mechanism in the etiopathogenesis of various diseases, including periodontal diseases, oral potentially malignant disorders, and squamous cell carcinoma of the oral cavity. Thioredoxin-1 (Trx-1), which acts as a redox regulator, plays a crucial role in the body’s antioxidative protection, inflammation, apoptosis processes and tumor growth. The detection of Trx-1 in saliva may serve as a promising non-invasive method for early diagnostics and prognosis in the diseases of the oral cavity.
Citation	Sathish S, Jain A, Nigam H, Singh V, Malik U. Salivary thioredoxin-1 as a non-invasive redox biomarker in oral diseases. World J Clin Cases 2026; In press DOI: https://doi.org/10.12998/wjcc.123160
PDF	123160-in-press.pdf

Received	2026-05-11 06:42
Peer-Review Started	2026-05-11 06:43
First Decision by Editorial Office Director	2026-06-10 03:03
Return for Revision	2026-06-10 03:03
Revised	2026-06-22 11:00
Publication Fee Transferred
Second Decision by Editor	2026-06-30 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-30 06:47
Articles in Press	2026-06-30 06:47
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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