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Articles in Press
6/30/2026 5:23:45 AM | Browse: 10 | Download: 1
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Lymph node metastasis in early gastric cancer: A review of risk stratification and surgical decision-making
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Min-Tian Xia, Quan Zhou, He Han, Dong Zhang and Xin Fan |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiangsu Commission of Health |
No. LKZ2023012 |
| Zhenjiang Gastrointestinal Tumor Clinical Key Laboratory |
No. SS2023011 |
| New Technology and New Programs of Jiangsu University Hospital |
No. xjs2024201 |
| Science and Technology Planning Project of Zhenjiang City |
No. SH2025001 |
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| Corresponding Author |
Xin Fan, Chief Physician, Department of Gastrointestinal Surgery, Affiliated Hospital of Jiangsu University, No. 438 Jiefang Road, Jingkou District, Zhenjiang 212000, Jiangsu Province, China. drfanxin@163.com |
| Key Words |
Early gastric cancer; Lymph node metastasis; Risk assessment; Imaging diagnosis; Artificial intelligence |
| Core Tip |
Lymph node metastasis remains the central factor guiding treatment selection in early gastric cancer, but its prediction before treatment is still unreliable. This review summarizes the biological basis of lymph node metastasis, including epithelial-mesenchymal transition, lymphangiogenesis, and immune regulation, and evaluates current diagnostic approaches such as imaging, sentinel lymph node mapping, biomarkers, and artificial intelligence. The main message is that no single method can exclude lymph node metastasis with sufficient confidence. Integrated risk stratification using clinical, imaging, and molecular information is needed to support individualized treatment decisions in early gastric cancer. |
| Citation |
Xia MT, Zhou Q, Han H, Zhang D, Fan X. Lymph node metastasis in early gastric cancer: A review of risk stratification and surgical decision-making. World J Gastrointest Oncol 2026; In press
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| PDF |
123261-in-press.pdf
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Received |
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2026-05-22 11:26 |
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Peer-Review Started |
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2026-05-22 11:26 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-06-16 08:09 |
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Revised |
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2026-06-18 09:32 |
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Publication Fee Transferred |
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2026-06-24 09:57 |
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Second Decision by Editor |
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2026-06-30 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-30 05:23 |
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Articles in Press |
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2026-06-30 05:23 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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