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Publication Name World Journal of Hepatology
Manuscript ID 123278
DOI 10.4254/wjh.123278
Country Mexico
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Prevalence and risk factors for metabolic dysfunction-associated steatotic liver disease and fibrosis in recently diagnosed type 2 diabetes
Manuscript Source Invited Manuscript
All Author List Astrid Ruiz-Margáin, Oscar Manuel Fierro-Angulo, Jose Alberto Gonzalez-Regueiro, Sergio Cesar Hernández-Jiménez, Ana Cristina García-Ulloa, Victoria Landa-Anell, Fernando Bril, Berenice Montserrat Roman-Calleja, Regina Romo-Arellano, Ariana Pereira-García, Naga Chalasani and Ricardo Ulises Macias-Rodriguez
Funding Agency and Grant Number
Corresponding Author Ricardo Ulises Macias-Rodriguez, Associate Professor, MD, PhD, Research Assistant Professor, Division of Hepatology and Liver Transplant, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ), Av. Vasco de Quiroga 15, Col. Belisario Dominguez Secc. XVI, Mexico 14080, Ciudad de México, Mexico. ricardo.maciasr@incmnsz.mx
Key Words Metabolic dysfunction-associated steatotic liver disease; Type 2 diabetes mellitus; Steatotic liver disease; Liver fibrosis
Core Tip There is scarce data specifically evaluating the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) and liver fibrosis in patients with recent-onset type 2 diabetes (< 5 years since diagnosis) and without micro or macrovascular complications. The Hispanic population is regarded as high-risk for metabolic diseases, including MASLD. We found a high prevalence of MASLD, affecting 41.4% of the study population, with 10% presenting clinically significant liver fibrosis (liver stiffness measurement ≥ 8 kPa) and 3% having cirrhosis. Our findings support incorporating liver health screening into the routine evaluation of patients with type 2 diabetes mellitus from diagnosis, even in those with good glycemic control and without chronic complications.
Citation Ruiz-Margáin A, Fierro-Angulo OM, González-Regueiro JA, Hernández-Jiménez SC, García-Ulloa AC, Landa-Anell V, Bril F, Roman-Calleja BM, Romo-Arellano R, Pereira-García A, Chalasani N, Macías-Rodríguez RU. Prevalence and risk factors for metabolic dysfunction-associated steatotic liver disease and fibrosis in recently diagnosed type 2 diabetes. World J Hepatol 2026; In press
PDF 123278-in-press.pdf
Received
2026-05-13 07:30
Peer-Review Started
2026-05-13 07:33
First Decision by Editorial Office Director
2026-06-12 14:17
Return for Revision
2026-06-12 14:17
Revised
2026-06-26 18:29
Publication Fee Transferred
Second Decision by Editor
2026-07-30 02:32
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-30 10:40
Articles in Press
2026-07-30 10:40
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com