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Publication Name World Journal of Critical Care Medicine
Manuscript ID 123294
DOI 10.5492/wjccm.123294
Country India
Category Biochemistry & Molecular Biology
Manuscript Type Observational Study
Article Title Evaluation of serum procalcitonin levels and their diagnostic utility in sepsis-associated acute kidney injury
Manuscript Source Invited Manuscript
All Author List Pradnya S Dhotre, Shree V Dhotre, Dipti B Sanakal and Basavraj S Nagoba
Funding Agency and Grant Number
Corresponding Author Basavraj S Nagoba, Professor, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Vishwanathpuram, Ambajogai Road, Latur 413531, Maharashtra, India. basavraj.nagoba@mimsr.edu.in
Key Words Sepsis; Acute kidney injury; Procalcitonin; Biomarkers; Critical care
Core Tip Sepsis-associated acute kidney injury (SA-AKI) is a frequent and life-threatening complication in critically ill patients, making early risk stratification essential. This observational study demonstrates that elevated admission serum procalcitonin levels are significantly associated with SA-AKI and identifies a clinically useful cutoff value of ≥ 5.5 ng/mL with good diagnostic accuracy (area under the curve 0.82). Given its widespread availability in routine clinical practice, procalcitonin may serve as a practical adjunctive biomarker for early identification and risk stratification of patients with SA-AKI, particularly in resource-limited healthcare settings.
Citation Dhotre PS, Dhotre SV, Sanakal DB, Nagoba BS. Evaluation of serum procalcitonin levels and their diagnostic utility in sepsis-associated acute kidney injury. World J Crit Care Med 2026; In press
PDF 123294-in-press.pdf
Received
2026-05-14 07:35
Peer-Review Started
2026-05-14 07:35
First Decision by Editorial Office Director
Return for Revision
2026-07-08 06:33
Revised
2026-07-10 08:02
Publication Fee Transferred
Second Decision by Editor
2026-09-03 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-04 09:15
Articles in Press
2026-09-04 09:15
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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