Publication Name	World Journal of Cardiology
Manuscript ID	123414
Country	China

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Cohort Study
Article Title	Triglyceride-glucose index and all-cause mortality in patients with chronic severe heart failure
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Feng Li, Xin Wang, Yuan Zhang, Jia Liu, Jia-Mei Liu, Mu-Lei Chen, Lin Zhao and Lin-Ying Shi
Funding Agency and Grant Number	Funding Agency Grant Number Noncommunicable Chronic Diseases-National Science and Technology Major Project 2024ZD0522006
Corresponding Author	Lin-Ying Shi, Heart Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongti South Road, Chaoyang District, Beijing 100020, China. sly197965@sina.cn
Key Words	Triglyceride-glucose index; Chronic severe heart failure; All-cause mortality; Insulin resistance; N-terminal pro-brain natriuretic peptide; Prognosis
Core Tip	In patients with chronic severe heart failure, the triglyceride-glucose (TyG) index independently predicts 5-year mortality but has only modest discriminative ability (area under the curve = 0.577). It adds minimal prognostic value beyond N-terminal pro-brain natriuretic peptide (NT-proBNP) and should not replace it in well-resourced settings. However, in resource-limited settings where NT-proBNP is unavailable, the TyG index may serve as a low-cost metabolic alert signal.
Citation	Li XF, Wang X, Zhang Y, Liu J, Liu JM, Chen ML, Zhao L, Shi LY. Triglyceride-glucose index and all-cause mortality in patients with chronic severe heart failure. World J Cardiol 2026; In press

Received	2026-05-19 07:50
Peer-Review Started	2026-05-19 07:50
First Decision by Editorial Office Director
Return for Revision	2026-07-14 03:34
Revised	2026-07-26 14:08
Publication Fee Transferred	2026-09-13 09:05
Second Decision by Editor	2026-09-21 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-21 09:20
Articles in Press	2026-09-21 09:20
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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