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Articles in Press
11/5/2026 5:29:46 AM | Browse: 7 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Identification of long non-coding RNA NUSAP1 as a novel biomarker associated with colorectal cancer progression and metastasis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Sheng-Hu Zhou, Jia Wang, Zong-Ying Jiang, Qi Huang, Ya-Qin He and Jin-Hai Tian |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Key Research and Development Program Project of Ningxia Province |
2021BEG03089 |
| Natural Science Foundation of Ningxia Province |
2021AAC03380 |
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| Corresponding Author |
Jin-Hai Tian, PhD, Institute of Medical Sciences, General Hospital of Ningxia Medical University, No. 804 Shengli Street, Xingqing District, Yinchuan 750004, Ningxia Hui Autonomous Region, China. smjinhai@126.com |
| Key Words |
Colorectal cancer; Long non-coding RNA NUSAP1; Biomarker; Cell proliferation; Metastasis |
| Core Tip |
Long non-coding RNA (lncRNA) NUSAP1 was significantly upregulated in colorectal cancer (CRC) tissues and cell lines and was closely associated with larger tumor size, higher grade, advanced tumor-node-metastasis stage, and lymph node metastasis. Its expression showed strong positive correlations with serum carcinoembryonic antigen and carbohydrate antigen 19-9 levels and demonstrated good diagnostic performance for CRC (area under the curve: 0.849; sensitivity: 93.66%, specificity: 72.54%). Functional assays revealed that lncRNA NUSAP1 promotes tumor cell proliferation, migration, and invasion while inhibiting apoptosis. These findings suggest lncRNA NUSAP1 acts as an oncogenic regulator and may serve as a potential diagnostic biomarker for CRC. |
| Citation |
Zhou SH, Wang J, Jiang ZY, Huang Q, He YQ, Tian JH. Identification of long non-coding RNA NUSAP1 as a novel biomarker associated with colorectal cancer progression and metastasis. World J Gastrointest Oncol 2026; In press
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| PDF |
123429-in-press.pdf
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Received |
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2026-05-19 07:27 |
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Peer-Review Started |
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2026-05-19 07:30 |
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First Decision by Editorial Office Director |
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2026-06-01 03:17 |
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Return for Revision |
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2026-06-01 03:17 |
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Revised |
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2026-06-22 07:12 |
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Publication Fee Transferred |
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2026-07-07 07:00 |
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Second Decision by Editor |
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2026-11-05 03:30 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-11-05 05:29 |
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Articles in Press |
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2026-11-05 05:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
