Publication Name	World Journal of Clinical Oncology
Manuscript ID	123454
DOI	10.5306/wjco.123454
Country	China

Category	Oncology
Manuscript Type	Case Report
Article Title	Transcatheter arterial embolization plus chemo targeted therapy for advanced hepatocellular carcinoma with 50-month: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Si-Lei Yu, Jin-E Liu, Chun-Ying Li, Hao Ling, Hai-Yun Tao and Yong-Qi Shen
Funding Agency and Grant Number	Funding Agency Grant Number Liuzhou Municipal Bureau of Science and Technology: Clinical Study of TAE Sequential Anlotinib Combined with Oxaliplatin plus Raltitrexed in the Treatment of Advanced Hepatocellular Carcinoma 2019BJ10613
Corresponding Author	Yong-Qi Shen, Chief Physician, MD, Department of Oncology, Liutie Central Hospital, No. 14 Limin Community, Fei'e Road, Liunan District, Liuzhou 545007, Guangxi Zhuang Autonomous Region, China. gxnnsyq@163.con
Key Words	Hepatocellular carcinoma; Transcatheter arterial embolization; Oxaliplatin; Raltitrexed; Anlotinib; Case report
Core Tip	This case reports a 52 year old patient diagnosed with hepatocellular carcinoma (CNLC stage IIIB) complicated by active clonorchiasis—an immunotherapy contraindication. The patient received transcatheter arterial embolization followed by sequential oxaliplatin, raltitrexed, and anlotinib, achieving partial response and progression free survival exceeding 50 months. The regimen may offer a viable alternative for immunotherapy ineligible advanced hepatocellular carcinoma patients, though long term efficacy requires further validation.
Citation	Yu SL, Liu JE, Li CY, Ling H, Tao HY, Shen YQ. Transcatheter arterial embolization plus chemo targeted therapy for advanced hepatocellular carcinoma with 50-month: A case report and review of literature. World J Clin Oncol 2026; In press DOI: https://doi.org/10.5306/wjco.123454
PDF	123454-in-press.pdf

Received	2026-05-19 07:28
Peer-Review Started	2026-05-19 07:30
First Decision by Editorial Office Director	2026-05-26 05:58
Return for Revision	2026-06-25 03:11
Revised	2026-07-21 15:06
Publication Fee Transferred	2026-08-01 08:45
Second Decision by Editor	2026-08-20 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-20 08:43
Articles in Press	2026-08-20 08:43
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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