Publication Name	World Journal of Orthopedics
Manuscript ID	123460
DOI	10.5312/wjo.123460
Country	Russia

Category	Sport Sciences
Manuscript Type	Observational Study
Article Title	New paradigms for identifying predisposition to bone injuries in young athletes: Collecting main significant keys for rapid diagnostics
Manuscript Source	Invited Manuscript
All Author List	Maria V Sankova, Evgeny E Achkasov, Vladimir N Nikolenko, Marine V Oganesyan, Negoriya A Rizaeva, Aleksey V Sankov, Lucas A S Pires, Tatyana S Zharikova and Yury O Zharikov
Funding Agency and Grant Number
Corresponding Author	Yury O Zharikov, Associate Professor, MD, PhD, Department of Human Anatomy and Histology, Sechenov First Moscow State Medical University (Sechenov University), Mokhovaya Street, 11s10, Moscow 125009, Moscow 125009, Russia. dr_zharikov@mail.ru
Key Words	Sports medicine; Bone injuries; Dysplastic re-injury threshold for bone re-injury incidence; Bone re-injury risk; Identifying predisposition to bone injuries; Bone injury prevention; Rapid screening method
Core Tip	Repeated bone injuries in young athletes are caused by underlying connective tissue dysplasia (CTD), not just injury. While individual dysplastic signs (for example, arachnodactyly, chest deformities, Gothic palate) do not have sufficient diagnostic accuracy, their combined severity determines the threshold for repeated dysplastic injury at 44.2 scores on the CTD scale-a new indicator of predisposition to bone injuries. This threshold allows for rapid risk stratification without molecular genetic testing, supporting individual choice of sport and preventive strategies. A complex phenotype consisting of ten easily identifiable external signs is a practical screening tool for sports physicians, allowing them to maintain the health of the musculoskeletal system in youth.
Citation	Sankova MV, Achkasov EE, Nikolenko VN, Oganesyan MV, Rizaeva NA, Sankov AV, Pires LAS, Zharikova TS, Zharikov YO. New paradigms for identifying predisposition to bone injuries in young athletes: Collecting main significant keys for rapid diagnostics. World J Orthop 2026; In press DOI: https://doi.org/10.5312/wjo.123460
PDF	123460-in-press.pdf

Received	2026-05-20 07:37
Peer-Review Started	2026-05-20 07:37
First Decision by Editorial Office Director
Return for Revision	2026-06-17 01:15
Revised	2026-07-05 09:11
Publication Fee Transferred
Second Decision by Editor	2026-07-17 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-17 08:16
Articles in Press	2026-07-17 08:16
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-5836 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com