Publication Name	World Journal of Gastroenterology
Manuscript ID	123590
DOI	10.3748/wjg.123590
Country	China

Category	Medicine, General & Internal
Manuscript Type	Case Report
Article Title	Gilbert syndrome masked by recurrent choledocholithiasis: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Hao Cheng, Lin-Hui Hu, Gui-Qiang Wang, Na Huo and Yan Wang
Funding Agency and Grant Number
Corresponding Author	Yan Wang, Department of Infectious Diseases, Peking University First Hoepital, No.8, XiShiKu Street, XiCheng District Beijing 100034, China, Beijing 100034, China. wangyanwang@bjmu.edu.cn
Key Words	Gilbert syndrome; UGT1A1; Choledocholithiasis; Pigment stones; Recurrent; Case report
Core Tip	Gilbert syndrome (GS) is generally regarded as a benign hereditary disorder, but its role in pigment stone formation and recurrent biliary disease may be underestimated. This case demonstrates that GS can be masked by recurrent choledocholithiasis and prolonged obstructive jaundice, leading to diagnostic uncertainty and repeated interventions. Recognition of the interaction between impaired bilirubin metabolism and biliary obstruction is essential. Genetic confirmation of GS in selected patients with unexplained persistent hyperbilirubinemia may help guide individualized management and avoid unnecessary invasive procedures.
Citation	Cheng H, Hu LH, Wang GQ, Huo N, Wang Y. Gilbert syndrome masked by recurrent choledocholithiasis: A case report. World J Gastroenterol 2026; In press DOI: https://doi.org/10.3748/wjg.123590
PDF	123590-in-press.pdf

Received	2026-05-25 07:38
Peer-Review Started	2026-05-25 07:38
First Decision by Editorial Office Director
Return for Revision	2026-06-23 06:19
Revised	2026-07-07 01:51
Publication Fee Transferred	2026-07-19 15:01
Second Decision by Editor	2026-09-02 02:54
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-04 09:34
Articles in Press	2026-09-04 09:34
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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