Publication Name	World Journal of Translational Medicine
Manuscript ID	123615
DOI	10.5528/wjtm.123615
Country	Japan

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Arterial stiffness and endothelial dysfunction in diabetes mellitus
Manuscript Source	Invited Manuscript
All Author List	Tomoyuki Kabutoya
Funding Agency and Grant Number
Corresponding Author	Tomoyuki Kabutoya, Associate Professor, Head, Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke 3290498, Tochigi, Japan. kabu@jichi.ac.jp
Key Words	Cardiovascular disease; Arterial stiffness; Endothelial dysfunction; Cardio ankle vascular index; Pulse wave velocity; Flow mediated dilation; Reactive hyperemia-peripheral arterial tonometry; Subclinical vascular damage; Cardiovascular risk stratification
Core Tip	Diabetes mellitus accelerates vascular aging through the concurrent progression of arterial stiffness and endothelial dysfunction, both of which contribute independently to cardiovascular risk. Noninvasive vascular indices - including pulse wave velocity, the cardio-ankle vascular index, flow mediated dilation, and reactive hyperemia-peripheral arterial tonometry - capture distinct but complementary aspects of diabetic vascular pathology. These measures are not interchangeable; rather, their integrated assessment may enhance early detection of subclinical vascular damage and improve cardiovascular risk stratification beyond traditional risk factors in patients with diabetes.
Citation	Kabutoya T. Arterial stiffness and endothelial dysfunction in diabetes mellitus. World J Transl Med 2026; In press DOI: https://doi.org/10.5528/wjtm.123615
PDF	123615-in-press.pdf

Received	2026-05-26 01:27
Peer-Review Started	2026-06-05 05:52
First Decision by Editorial Office Director
Return for Revision	2026-07-07 09:30
Revised	2026-07-18 08:56
Publication Fee Transferred
Second Decision by Editor	2026-07-28 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-28 12:20
Articles in Press	2026-07-28 12:20
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6132 (online)
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