Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	123631
DOI	10.4251/wjgo.123631
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Combined low muscle mass and body mass index for prognosis in esophageal squamous cell carcinoma patients receiving immunochemoradiotherapy
Manuscript Source	Unsolicited Manuscript
All Author List	Ling Xiao, Lin-Jie Li, Jia-Hua Lyu, Shi-Chuan Zhang and Long Liang
Funding Agency and Grant Number
Corresponding Author	Long Liang, Associate Chief Physician, Department of Radiation, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, No. 55 Section 4, Renmin South Road, Chengdu 610041, Sichuan Province, China. lianglong@scszlyy.org.cn
Key Words	Esophageal squamous cell carcinoma; Immunochemoradiotherapy; Skeletal muscle index; Low muscle mass; Body mass index
Core Tip	In this retrospective study of 105 patients with esophageal squamous cell carcinoma receiving immunochemoradiotherapy, we found that the prognostic value of low muscle mass is highly dependent on body mass index (BMI). Low muscle mass served as a strong independent adverse prognostic factor only in patients with BMI ≥ 22.0 kg/m2, but showed no predictive efficacy in individuals with lower BMI, demonstrating marked BMI-dependent heterogeneity. This finding provides a novel basis for personalized risk stratification and clinical management of esophageal squamous cell carcinoma patients.
Citation	Xiao L, Li LJ, Lyu JH, Zhang SC, Liang L. Combined low muscle mass and body mass index for prognosis in esophageal squamous cell carcinoma patients receiving immunochemoradiotherapy. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.123631
PDF	123631-in-press.pdf

Received	2026-05-25 07:18
Peer-Review Started	2026-05-25 07:18
First Decision by Editorial Office Director
Return for Revision	2026-07-06 10:57
Revised	2026-07-20 01:48
Publication Fee Transferred	2026-08-01 09:41
Second Decision by Editor	2026-09-03 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-04 09:35
Articles in Press	2026-09-04 09:35
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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