Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	123659
DOI	10.4240/wjgs.123659
Country	China

Category	Surgery
Manuscript Type	Retrospective Study
Article Title	Laparoscopic surgery for severe appendicitis in children: An effect and safety analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Zhong-Ya Xu, Hui Ye and Si-Hai Wu
Funding Agency and Grant Number
Corresponding Author	Si-Hai Wu, Surgical Intensive Care Unit, Children’s Hospital of Nanjing Medical University, No. 8 Jiangdong South Road, Jianye District, Nanjing 210000, Jiangsu Province, China. for_sea@163.com
Key Words	Laparoscopic surgery; Severe appendicitis in children; Effect; Safety; Retrospective analysis
Core Tip	This study assesses the effectiveness and safety of conventional open appendectomy compared to laparoscopic appendectomy in managing severe appendicitis, including gangrenous appendicitis, perforated appendicitis, and periappendiceal abscess, in children aged 6-12 years. Laparoscopic surgery yields superior clinical benefits, as evidenced by smaller incisions, shorter surgical durations, reduced intraoperative bleeding, lower requirements for postoperative analgesics, faster gastrointestinal functional recovery, and decreased length of hospital stay, all without incurring additional hospitalization costs. Furthermore, laparoscopic surgery significantly mitigates inflammation and stress responses while actively regulating postoperative gastrointestinal hormone levels.
Citation	Xu ZY, Ye H, Wu SH. Laparoscopic surgery for severe appendicitis in children: An effect and safety analysis. World J Gastrointest Surg 2026; In press DOI: https://doi.org/10.4240/wjgs.123659
PDF	123659-in-press.pdf

Received	2026-06-02 10:37
Peer-Review Started	2026-06-02 10:37
First Decision by Editorial Office Director
Return for Revision	2026-06-23 08:58
Revised	2026-07-02 03:39
Publication Fee Transferred	2026-07-04 04:47
Second Decision by Editor	2026-07-17 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-17 07:53
Articles in Press	2026-07-17 07:53
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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