Publication Name	World Journal of Gastroenterology
Manuscript ID	123678
DOI	10.3748/wjg.123678
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Observational Study
Article Title	Triglyceride-glucose and body shape index as metabolic-morphometric markers for metabolic dysfunction-associated steatotic liver disease identification across glycemic spectrum
Manuscript Source	Unsolicited Manuscript
All Author List	Rong-Dong-Qing Shi, Wen-Hao Zhang, Kui Chen, Xin-Yuan Ye, Qing Xu, Xian-Ming Li, Gui-Hua Yu, Si-Hui Luo and Yu Ding
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82300904 National Natural Science Foundation of China 82100857 Anhui Provincial Health Research Project AHWJ2024Aa20543
Corresponding Author	Yu Ding, Department of Endocrinology and Metabolism, The First Affiliated Hospital of USTC, University of Science and Technology of China, No. 17 Lujiang Road, Hefei 230001, Anhui Province, China. yuding6815@163.com
Key Words	Triglyceride-glucose index combined with a body shape index; Metabolic dysfunction-associated steatotic liver disease; Glucose metabolism; Risk stratification; Non-invasive biomarker
Core Tip	Metabolic dysfunction-associated steatotic liver disease (MASLD) requires accessible, non-invasive biomarkers for early risk stratification. This study evaluated the triglyceride-glucose index combined with a body shape index (TyG-ABSI), a composite marker of insulin resistance and central adiposity, in 7413 Chinese adults undergoing health examinations across the glycemic spectrum. TyG-ABSI was independently associated with MASLD in normal glucose regulation, prediabetes, and diabetes mellitus, with the strongest discriminative performance before overt diabetes developed. These findings suggest that TyG-ABSI holds potential as an accessible, laboratory-based marker for identifying cross-sectional MASLD risk, particularly during the metabolically vulnerable and actionable prediabetic stage.
Citation	Shi RDQ, Zhang WH, Chen K, Ye XY, Xu Q, Li XM, Yu GH, Luo SH, Ding Y. Triglyceride-glucose and body shape index as metabolic-morphometric markers for metabolic dysfunction-associated steatotic liver disease identification across glycemic spectrum. World J Gastroenterol 2026; In press DOI: https://doi.org/10.3748/wjg.123678
PDF	123678-in-press.pdf

Received	2026-05-28 06:24
Peer-Review Started	2026-05-28 06:24
First Decision by Editorial Office Director
Return for Revision	2026-07-23 02:29
Revised	2026-08-03 14:35
Publication Fee Transferred	2026-10-09 05:04
Second Decision by Editor	2026-10-26 07:15
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-26 09:08
Articles in Press	2026-10-26 09:08
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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