Publication Name	World Journal of Gastroenterology
Manuscript ID	123704
DOI	10.3748/wjg.123704
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Narrow-band imaging-modified Kyoto score predicts pathological upgrading after endoscopic submucosal dissection in gastric intraepithelial neoplasia
Manuscript Source	Unsolicited Manuscript
All Author List	Tao Chen, An-Qiang Feng, Wei-Feng Zhang, Ni-Yi Dang, Feng Ye and Guo-Xin Zhang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 82470593 General Project of the Development Fund of the Affiliated Hospital of Xuzhou Medical University No. XYFM202334
Corresponding Author	Guo-Xin Zhang, PhD, Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. nanjingmedical@163.com
Key Words	Gastric intraepithelial neoplasia; Pathological upgrading; Narrow-band imaging; Kyoto Gastritis Score; Endoscopic submucosal dissection; Intestinal metaplasia; Helicobacter pylori
Core Tip	This prospective study evaluated a narrow-band imaging-magnifying endoscopy-modified Kyoto Gastritis Score for predicting pathological upgrading after endoscopic submucosal dissection in gastric intraepithelial neoplasia. The modified score replaces white-light assessment of intestinal metaplasia with narrow-band imaging-magnifying endoscopy features, improving discrimination over the conventional score (area under the curve: 0.862 vs 0.769) and remaining independently associated with upgrading. A cutoff of ≥ 4 provided a negative predictive value of 83.22%, supporting low-risk identification and surveillance planning across Helicobacter pylori infection subgroups, although multicenter validation remains necessary.
Citation	Chen T, Feng AQ, Zhang WF, Dang NY, Ye F, Zhang GX. Narrow-band imaging-modified Kyoto score predicts pathological upgrading after endoscopic submucosal dissection in gastric intraepithelial neoplasia. World J Gastroenterol 2026; In press DOI: https://doi.org/10.3748/wjg.123704
PDF	123704-in-press.pdf

Received	2026-05-29 07:23
Peer-Review Started	2026-05-29 07:24
First Decision by Editorial Office Director	2026-06-10 09:20
Return for Revision	2026-06-10 09:20
Revised	2026-07-10 05:49
Publication Fee Transferred	2026-07-20 08:34
Second Decision by Editor	2026-07-24 03:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-28 12:04
Articles in Press	2026-07-28 12:04
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Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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