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Publication Name World Journal of Translational Medicine
Manuscript ID 123849
DOI 10.5528/wjtm.123849
Country China
Category Gastroenterology & Hepatology
Manuscript Type Frontier
Article Title Heterogeneity-oriented multidisciplinary and super-minimally invasive precision treatment framework for locally advanced gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Qian-Qian Chen, Jia-Yan Zhou and En-Qiang Linghu
Funding Agency and Grant Number
Corresponding Author En-Qiang Linghu, Chief Physician, MD, PhD, Professor, Department of Gastroenterology, The First Medical Center, General Hospital of the Chinese PLA, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. linghuenqiang@vip.sina.com
Key Words Locally advanced gastric cancer; Intratumoral heterogeneity; Multidisciplinary treatment; Super minimally invasive surgery; Precision oncology
Core Tip Heterogeneity-oriented multidisciplinary team planning and super minimally invasive precision resection is an investigational heterogeneity-oriented framework, not a substitute for standard D2 gastrectomy. The central requirement of this concept is that any function-preserving local intervention must also achieve adequate control of the full gastric wall, the serosal-peritoneal interface, and regional lymph nodes. Endoscopy alone cannot meet these requirements in cT3-T4a disease; therefore, implementation would require a carefully selected, combined endoscopic-laparoscopic pathway and prospective validation.
Citation Chen QQ, Zhou JY, Linghu EQ. Heterogeneity-oriented multidisciplinary and super-minimally invasive precision treatment framework for locally advanced gastric cancer. World J Transl Med 2026; In press
PDF 123849-in-press.pdf
Received
2026-06-01 08:08
Peer-Review Started
2026-06-01 08:09
First Decision by Editorial Office Director
Return for Revision
2026-07-09 03:08
Revised
2026-07-18 08:27
Publication Fee Transferred
Second Decision by Editor
2026-09-02 02:54
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-04 09:42
Articles in Press
2026-09-04 09:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-6132 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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