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8/25/2026 9:33:09 AM | Browse: 32 | Download: 10
Publication Name World Journal of Diabetes
Manuscript ID 123878
DOI 10.4239/wjd.123878
Country China
Category Endocrinology & Metabolism
Manuscript Type Observational Study
Article Title Re-evaluated associations of quantitative-computed tomography measured abdominal and ectopic fat with impaired glucose metabolism in overweight/obese Chinese
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Li Ma, Yang Liu, Bo-Han Li, Hui-Chen Zhao, Yan-Pei Sun, He-Li Han, Wan-Jiang Yu, Hua Lin, Wei-Na Mu and Yuan-Tao Liu
Funding Agency and Grant Number
Funding Agency Grant Number
the Natural Science Foundation of Shandong No. ZR2022MH086
Corresponding Author Yuan-Tao Liu, PhD, Professor, Department of Clinical Nutrition, Department of Endocrinology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, No. 758 Hefei Road, Shibei District, Qingdao 266035, Shandong Province, China. sduliuyuantao@126.com
Key Words Obesity; Fat distribution; Impaired glucose metabolism; Type 2 diabetes; Metabolic disease
Core Tip This cross-sectional study of overweight/obese Chinese adults using quantitative-computed tomography re-evaluated sex-specific associations of abdominal and ectopic fat with impaired glucose metabolism (IGM). Hepatic fat fraction and visceral adipose tissue were independently associated with IGM in both sexes, with odds ratios reaching 5.24-6.45 for hepatic fat fraction and 3.29-6.56 for visceral adipose tissue. Notably, higher subcutaneous adipose tissue was associated with lower IGM odds only in males (odds ratio = 0.13). These findings highlight that sex differences in abdominal fat distribution may contribute to heterogeneity in glucose metabolism disorders.
Citation Ma XL, Liu Y, Li BH, Zhao HC, Sun YP, Han HL, Yu WJ, Lin H, Mu WN, Liu YT. Re-evaluated associations of quantitative-computed tomography measured abdominal and ectopic fat with impaired glucose metabolism in overweight/obese Chinese. World J Diabetes 2026; In press
PDF 123878-in-press.pdf
Received
2026-06-08 08:59
Peer-Review Started
2026-06-16 10:09
First Decision by Editorial Office Director
Return for Revision
2026-07-08 08:55
Revised
2026-07-20 08:04
Publication Fee Transferred
2026-08-02 11:15
Second Decision by Editor
2026-08-10 09:32
Second Decision by Editor-in-Chief
2026-08-14 09:36
Final Decision by Editorial Office Director
2026-08-25 09:33
Articles in Press
2026-08-25 09:33
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9358 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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