Publication Name	World Journal of Clinical Cases
Manuscript ID	123883
Country	India

Category	Infectious Diseases
Manuscript Type	Editorial
Article Title	From contaminant to catastrophe: Applying integrated antimicrobial stewardship DIA model in a case
Manuscript Source	Invited Manuscript
All Author List	Prasan Kumar Panda and Fatima Khan
Funding Agency and Grant Number
Corresponding Author	Prasan Kumar Panda, Division of Internal Medicine, All India Institute of Medical Sciences, College Block, Rishikesh 249203, Uttarākhand, India. motherprasanna@rediffmail.com
Key Words	Integrated antimicrobial stewardship; Corynebacterium striatum; Infective endocarditis; Diagnostic stewardship; Device stewardship; Bloodstream infection; Antimicrobial resistance; Healthcare-associated infection; Society of Antimicrobial Stewardship PractIces; PRESCRIBES framework
Core Tip	Corynebacterium striatum, often dismissed as a contaminant, can cause severe and fatal infections in immunocompromised and device-dependent patients. This case demonstrates that adverse outcomes frequently result not from antimicrobial failure alone but from delayed integration of diagnostic, microbiological, device, therapeutic, and administrative stewardship measures. Integrated antimicrobial stewardship (IAS) provides a comprehensive framework for timely recognition, source control, multidisciplinary coordination, and optimized patient management. Implementing stewardship models, such as Society of Antimicrobial Stewardship PractIces’s 42 IAS practice points in form of DIA model and the PRESCRIBES framework, may improve clinical outcomes and reduce the burden of antimicrobial resistance in complex healthcare-associated infections.
Citation	Panda PK, Khan F. From contaminant to catastrophe: Applying integrated antimicrobial stewardship DIA model in a case. World J Clin Cases 2026; In press

Received	2026-06-02 10:26
Peer-Review Started	2026-06-02 10:32
First Decision by Editorial Office Director
Return for Revision	2026-07-09 05:48
Revised	2026-07-11 04:29
Publication Fee Transferred
Second Decision by Editor	2026-07-24 03:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-27 10:01
Articles in Press	2026-07-27 10:01
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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