Publication Name	World Journal of Gastroenterology
Manuscript ID	123951
DOI	10.3748/wjg.123951
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Total bile acid better reflects the early biochemical biliary drainage response after endoscopic retrograde cholangiopancreatography
Manuscript Source	Unsolicited Manuscript
All Author List	Guo-Lin Liao, Hai-Xing Wei, Jian-Fu Qin, Fei Qin, Jie Wang, Shi-Quan Liu, Jie-An Huang and Meng-Bin Qin
Funding Agency and Grant Number
Corresponding Author	Meng-Bin Qin, Assistant Professor, Deputy Director, MD, Department of Gastroenterology, The Second Affiliated Hospital of Guangxi Medical University, No. 166 Daxuedong Road, Nanning 530007, Guangxi Zhuang Autonomous Region, China. dr.mmbin@hotmail.com
Key Words	Total bile acid; Bilirubin; Biliary drainage; Endoscopic retrograde cholangiopancreatography; Cholestasis; Postoperative monitoring
Core Tip	Bilirubin-based markers are commonly used to assess the biliary drainage response after therapeutic endoscopic retrograde cholangiopancreatography, but their early postoperative changes may be limited. In this real-world cohort, total bile acid (TBA) declined earlier and more markedly than direct and total bilirubin. Although gamma-glutamyl transferase and alkaline phosphatase also declined after drainage, their early changes were smaller than those of TBA. These findings support TBA as a responsive adjunctive marker of early biochemical recovery after biliary drainage.
Citation	Liao GL, Wei HX, Qin JF, Qin F, Wang J, Liu SQ, Huang JA, Qin MB. Total bile acid better reflects the early biochemical biliary drainage response after endoscopic retrograde cholangiopancreatography. World J Gastroenterol 2026; In press DOI: https://doi.org/10.3748/wjg.123951
PDF	123951-in-press.pdf

Received	2026-06-03 06:46
Peer-Review Started	2026-06-03 06:46
First Decision by Editorial Office Director	2026-06-15 07:40
Return for Revision	2026-06-15 07:40
Revised	2026-06-24 04:26
Publication Fee Transferred	2026-07-01 11:50
Second Decision by Editor	2026-07-17 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-17 03:23
Articles in Press	2026-07-17 03:23
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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