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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 123962
Country China
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Interferon therapy reduces incidence of hepatocellular carcinoma in patients with high risk of hepatitis B virus-related hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Miao Hao, Chen-Rui Liu, Meng Zhang, Xia-Qing Zhou, Zi-Cheng Jiang, Xiao-Hong Gao, Xin Zhang, Wen-Jun Wang, Yi-Kai Wang, Xiao-Li Jia, Ya-Ping Li and Shuang-Suo Dang
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Research and Development Program of China 2023 No. 2023YFC2308105
Natural Science Foundation of Shaanxi Province No. 2023-JC-YB-770
Corresponding Author Shuang-Suo Dang, Department of Infectious Diseases, The Second Affiliated Hospital of Xi’an Jiaotong University, No. 157 West 5th Road, Xi’an 710004, Shaanxi Province, China. dang212@126.com
Key Words Interferon; Nucleotides and nucleosides; Hepatocellular carcinoma; Hepatitis B virus; High-risk population for hepatocellular carcinoma; Chronic hepatitis B
Core Tip Based on this observational study, we compared the incidence of hepatocellular carcinoma (HCC) in high-risk hepatitis B virus-related HCC patients receiving interferon vs nucleoside/nucleotide analogues. For hepatitis B virus-infected individuals with high-risk factors for HCC, interferon therapy before progression to decompensated cirrhosis helps reduce the risk of HCC.
Citation Hao M, Liu CR, Zhang M, Zhou XQ, Jiang ZC, Gao XH, Zhang X, Wang WJ, Wang YK, Jia XL, Li YP, Dang SS. Interferon therapy reduces incidence of hepatocellular carcinoma in patients with high risk of hepatitis B virus-related hepatocellular carcinoma. World J Gastrointest Oncol 2026; In press
Received
2026-06-02 07:48
Peer-Review Started
2026-06-02 07:48
First Decision by Editorial Office Director
Return for Revision
2026-06-24 15:01
Revised
2026-07-22 13:54
Publication Fee Transferred
Second Decision by Editor
2026-09-01 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-01 08:16
Articles in Press
2026-09-01 08:16
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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