Publication Name	World Journal of Gastroenterology
Manuscript ID	123972
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Correspondence
Article Title	Letter to the Editor: Salidroside in ulcerative colitis - neuroimmune regulatory mechanisms and clinical translation prospects
Manuscript Source	Unsolicited Manuscript
All Author List	Yao-Feng Zhou, Jia-Wang Yan and Fu-Shan Tang
Funding Agency and Grant Number
Corresponding Author	Fu-Shan Tang, Full Professor, Clinical Pharmacy, Zunyi Medical University, No. 6 Xuefu West Road, Xinpu New District, Zunyi 563006, Guizhou Province, China. fstang@vip.163.com
Key Words	Ulcerative colitis; Salidroside; Cyclic adenosine monophosphate pathway; Protein Kinase A pathway; cAMP response element-binding protein pathway; Enteric glial cells; Neuro-glial-immune regulatory network
Core Tip	This article presents a novel perspective based on the “enteric neuro-glial-immune regulatory network” and elucidates the potential mechanisms by which salidroside exerts anti-inflammatory, immunomodulatory, and intestinal mucosal barrier-protective effects through the regulation of enteric glial cells. Furthermore, by discussing the challenges associated with clinical translation and formulation optimization strategies, this article explores the potential application of salidroside as a multi-target therapeutic agent for precision treatment of ulcerative colitis.
Citation	Zhou YF, Yan JW, Tang FS. Letter to the Editor: Salidroside in ulcerative colitis - neuroimmune regulatory mechanisms and clinical translation prospects. World J Gastroenterol 2026; In press

Received	2026-06-03 07:34
Peer-Review Started	2026-06-03 07:34
First Decision by Editorial Office Director
Return for Revision	2026-07-20 09:22
Revised	2026-07-28 11:40
Publication Fee Transferred
Second Decision by Editor	2026-08-31 03:15
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-31 08:18
Articles in Press	2026-08-31 08:18
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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