Publication Name	World Journal of Gastroenterology
Manuscript ID	124159
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Online calculators to predict severe Hirschsprung-associated enterocolitis after pull-through surgery for Hirschsprung disease: A multicenter retrospective study
Manuscript Source	Unsolicited Manuscript
All Author List	Jing-Feng Tang, Yun Zhou, Zhi-Bin Luo, Ze-Bing Zheng, Meng-Xin Zhang, Shui-Qing Chi, Guo-Qing Cao, Xi Zhang, Shuai Li, Bin Zhong and Shao-Tao Tang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 82571986 the Open Research Fund of Hubei Key Laboratory of Precision Radiation Oncology No. 2024ZLJZFL006
Corresponding Author	Shao-Tao Tang, Chief, PhD, Professor, Department of Pediatric Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. tshaotao83@hust.edu.cn
Key Words	Hirschsprung-associated enterocolitis; Hirschsprung disease; Nomogram; Prediction; Online calculator
Core Tip	This multicenter study introduces a novel nomogram and web-based calculator to predict severe Hirschsprung-associated enterocolitis following pull-through surgery. Unlike prior models, it specifically targets American Pediatric Surgical Association grade II and III Hirschsprung-associated enterocolitis. Integrating eight routine perioperative variables, it identifies postoperative intestinal obstruction as the strongest risk factor. Validated externally with excellent discrimination, this accessible tool empowers clinicians to individualize risk assessments. By identifying high-risk patients early, it facilitates targeted interventions and proactive decision-making, ultimately improving pediatric surgical outcomes.
Citation	Tang JF, Zhou Y, Luo ZB, Zheng ZB, Zhang MX, Chi SQ, Cao GQ, Zhang X, Li S, Zhong B, Tang ST. Online calculators to predict severe Hirschsprung-associated enterocolitis after pull-through surgery for Hirschsprung disease: A multicenter retrospective study. World J Gastroenterol 2026; In press

Received	2026-06-09 06:43
Peer-Review Started	2026-06-09 06:43
First Decision by Editorial Office Director
Return for Revision	2026-06-16 07:06
Revised	2026-06-29 16:33
Publication Fee Transferred	2026-07-19 13:36
Second Decision by Editor	2026-07-27 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-27 09:54
Articles in Press	2026-07-27 09:54
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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