Publication Name	World Journal of Psychiatry
Manuscript ID	124177
DOI	10.5498/wjp.124177
Country	China

Category	Psychiatry
Manuscript Type	Retrospective Cohort Study
Article Title	Effects of intermittent theta burst stimulation on behavioral and psychological symptoms of dementia in patients after cardiothoracic surgery
Manuscript Source	Unsolicited Manuscript
All Author List	Jing-Jing Ni, Wei Pan and Lin-Han Feng
Funding Agency and Grant Number	Funding Agency Grant Number Public Hospital Scientific Research Joint Fund Science and Technology Project No. 2025GLLH0279
Corresponding Author	Lin-Han Feng, MD, Department of Laboratory, Beijing Emergency General Hospital, No. 29 Nanli, Xiba, Beijing 100020, China. shuoguo052918@163.com
Key Words	Intermittent theta burst stimulation; Behavioral and psychological symptoms of dementia; Cardiothoracic surgery; Older adults; Cognitive function; Dorsolateral prefrontal cortex
Core Tip	Older patients after cardiothoracic surgery are at high risk of behavioral and psychological symptoms of dementia (BPSD), while effective non-pharmacological treatments remain limited. This retrospective cohort study showed that intermittent theta burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex was associated with reduced BPSD severity, improved cognitive function, and better daily living performance, with no statistically significant difference in adverse event rates between the two groups. Exploratory findings further suggested that enhanced gamma-band brain connectivity and reduced inflammatory cytokines may be involved in the therapeutic effects of iTBS. These results indicate that iTBS may be a safe and promising treatment option for postoperative BPSD in older adults.
Citation	Ni JJ, Pan W, Feng LH. Effects of intermittent theta burst stimulation on behavioral and psychological symptoms of dementia in patients after cardiothoracic surgery. World J Psychiatry 2026; In press DOI: https://doi.org/10.5498/wjp.124177
PDF	124177-in-press.pdf

Received	2026-07-14 11:45
Peer-Review Started	2026-07-14 11:45
First Decision by Editorial Office Director
Return for Revision	2026-08-05 03:46
Revised	2026-08-14 18:55
Publication Fee Transferred	2026-09-14 08:26
Second Decision by Editor	2026-10-09 03:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-09 09:38
Articles in Press	2026-10-09 09:38
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com