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Publication Name World Journal of Transplantation
Manuscript ID 124190
Country Greece
Category Transplantation
Manuscript Type Systematic Reviews
Article Title Addressing gender-based disparities in liver transplantation: A global analysis of surgical access and donor organ allocation
Manuscript Source Invited Manuscript
All Author List Sofia Rozani, Alexander Papadopoulos, Giorgos Smyrnis, Francesca Albanesi, Stavros P Papadakos, Efstathia Liatsou, Venkatesh Balaraman Sundararajan, Lorenzo Petagna, Georgia Rozani and Vasileios Vougas
Funding Agency and Grant Number
Corresponding Author Sofia Rozani, Academic Fellow, MD, PhD, Research Fellow, 2nd Department of Surgery, Aretaieio University Hospital, National and Kapodistrian University of Athens, Vas. Sofias Street 76, Athens 11528, Attikí, Greece. sofrozan@gmail.com
Key Words Liver transplantation; Model for end-stage liver disease; Transplantation; Gender disparities; Model for end-stage liver disease 3.0
Core Tip Sex- and gender-based disparities remain a significant challenge in liver transplantation despite advances in allocation systems. Female patients continue to experience lower transplant access, longer waiting times, and higher waitlist mortality due to multifactorial factors including model for end-stage liver disease-related creatinine bias, donor-recipient size mismatch, reduced access to exception points, and barriers in referral and evaluation pathways. Recent innovations, such as model for end-stage liver disease 3.0, sex-adjusted allocation models, living donor liver transplantation, and size-aware allocation strategies have improved equity but have not eliminated disparities yet. This review summarizes contemporary global evidence and highlights emerging approaches aimed at achieving fairer organ allocation and improved outcomes for female liver transplant candidates.
Citation Rozani S, Papadopoulos A, Smyrnis G, Albanesi F, Papadakos SP, Liatsou E, Balaraman Sundararajan V, Petagna L, Rozani G, Vougas V. Addressing gender-based disparities in liver transplantation: A global analysis of surgical access and donor organ allocation. World J Transplant 2026; In press
Received
2026-06-09 02:38
Peer-Review Started
2026-06-09 02:39
First Decision by Editorial Office Director
Return for Revision
2026-07-03 09:16
Revised
2026-07-15 17:14
Publication Fee Transferred
Second Decision by Editor
2026-07-24 03:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-27 09:52
Articles in Press
2026-07-27 09:52
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com